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转移性乳腺癌与年轻、中年和老年女性相关的生产力成本。

Productivity costs associated with metastatic breast cancer in younger, midlife, and older women.

机构信息

Department of Health Policy and Management, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.

Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.

出版信息

Cancer. 2020 Sep 15;126(18):4118-4125. doi: 10.1002/cncr.33077. Epub 2020 Jul 10.

Abstract

BACKGROUND

The objective of the current study was to estimate productivity costs due to metastatic breast cancer (mBC) via productive time lost among survivors and potential life-years lost from premature mortality among 3 age groups: younger (aged 18-44 years), midlife (aged 45-64 years), and older (aged ≥65 years) women.

METHODS

The authors estimated the number of work and home productivity days missed due to mBC by age group using data from the 2000 to 2016 National Health Interview Survey. Years of potential life lost (YPLL) due to mBC were calculated for each age group using 2015 National Vital Statistics System data. The authors valued both sources of lost productivity time using the Current Population Survey and prior studies.

RESULTS

The per-woman value of lost productive days (work and home) due to mBC ranged from $680 for older women to $5169 for younger women. In 2015, the value of lost work and home productivity days associated with mBC nationally was $67 million for younger women, $246 million for midlife women, and $66 million for older women. YPLL were highest among midlife women (403,786 life-years), followed by older women (248,522 life-years) and younger women (95,943 life-years). Midlife women were found to have the highest market value of YPLL ($4.1 billion), followed by younger women ($1.6 billion) and older women ($527 million).

CONCLUSIONS

The results of the current study demonstrated that mBC generates a high economic burden through lost productivity, especially among midlife women.

摘要

背景

本研究旨在通过对 3 个年龄组(18-44 岁、45-64 岁和≥65 岁)的幸存者因转移性乳腺癌(mBC)而失去的生产时间和因过早死亡而损失的潜在寿命年数,估算因 mBC 导致的生产力成本。

方法

本研究利用 2000 年至 2016 年全国健康访谈调查的数据,按年龄组估算因 mBC 而错过的工作和家庭生产天数。利用 2015 年国家生命统计系统数据计算每个年龄组因 mBC 导致的潜在寿命年损失(YPLL)。本研究使用当前人口调查和之前的研究来衡量这两种损失的生产时间价值。

结果

因 mBC 而导致的女性失去的生产时间(工作和家庭)的每位女性价值范围为老年女性 680 美元至年轻女性 5169 美元。2015 年,因 mBC 导致的全国年轻、中年和老年女性丧失工作和家庭生产力天数的价值分别为 6700 万美元、2.46 亿美元和 6600 万美元。中年女性的 YPLL 最高(403786 个生命年),其次是老年女性(248522 个生命年)和年轻女性(95943 个生命年)。中年女性的 YPLL 市场价值最高(41 亿美元),其次是年轻女性(16 亿美元)和老年女性(5.27 亿美元)。

结论

本研究结果表明,mBC 通过生产力损失带来了巨大的经济负担,尤其是对中年女性而言。

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