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增强骨向内生长到多孔钛结构中以改善牙种植体的骨整合:犬模型的初步研究。

Enhancement of Bone Ingrowth into a Porous Titanium Structure to Improve Osseointegration of Dental Implants: A Pilot Study in the Canine Model.

作者信息

Hong Ji-Youn, Ko Seok-Yeong, Lee Wonsik, Chang Yun-Young, Kim Su-Hwan, Yun Jeong-Ho

机构信息

Department of Periodontology, Periodontal-Implant Clinical Research Institute, School of Dentistry, Kyung Hee University, 26, Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Korea.

Department of Periodontology, College of Dentistry and Institute of Oral Bioscience, Jeonbuk National University, 567, Baekje-daero, Deokjin-gu, Jeonju-si, Jeollabuk-do 54896, Korea.

出版信息

Materials (Basel). 2020 Jul 8;13(14):3061. doi: 10.3390/ma13143061.

Abstract

A porous titanium structure was suggested to improve implant stability in the early healing period or in poor bone quality. This study investigated the effect of a porous structure on the osseointegration of dental implants. A total of 28 implants (14 implants in each group) were placed in the posterior mandibles of four beagle dogs at 3 months after extraction. The control group included machined surface implants with an external implant-abutment connection, whereas test group implants had a porous titanium structure added to the apical portion. Resonance frequency analysis (RFA); removal torque values (RTV); and surface topographic and histometric parameters including bone-to-implant contact length and ratio, inter-thread bone area and ratio in total, and the coronal and apical parts of the implants were measured after 4 weeks of healing. RTV showed a significant difference between the groups after 4 weeks of healing ( = 0.032), whereas no difference was observed in RFA. In the test group, surface topography showed bone tissue integrated into the porous structures. In the apical part of the test group, all the histometric parameters exhibited significant increases compared to the control group. Within the limitations of this study, enhanced bone growth into the porous structure was achieved, which consequently improved osseointegration of the implant.

摘要

有人提出一种多孔钛结构可在愈合早期或骨质较差的情况下提高种植体稳定性。本研究调查了多孔结构对牙种植体骨结合的影响。在4只比格犬拔牙后3个月时,将总共28枚种植体(每组14枚)植入下颌后牙区。对照组包括具有外部种植体-基台连接的机械加工表面种植体,而试验组种植体在根尖部分添加了多孔钛结构。愈合4周后,测量共振频率分析(RFA)、去除扭矩值(RTV)以及包括骨与种植体接触长度和比例、螺纹间骨面积及其占总面积的比例,以及种植体冠部和根尖部在内的表面形貌和组织计量学参数。愈合4周后,两组间RTV显示出显著差异(P = 0.032),而RFA未观察到差异。在试验组中,表面形貌显示骨组织融入多孔结构。在试验组根尖部分,与对照组相比,所有组织计量学参数均显著增加。在本研究的局限性内,实现了骨向多孔结构内的生长增强,从而改善了种植体的骨结合。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9394/7412235/8188490999ce/materials-13-03061-g001.jpg

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