卫生假说是否适用于 COVID-19 的易感性？
Does the hygiene hypothesis apply to COVID-19 susceptibility?
机构信息
Department of Biological Sciences, Indian Institute of Science Education and Research Mohali, Sector 81 SAS Nagar, Knowledge City PO Manauli, Mohali, 140360, Punjab, India.
Biomedical & Diagnostic Sciences, College of Veterinary Medicine, The University of Tennessee, Knoxville, TN, 37996-0845, USA.
出版信息
Microbes Infect. 2020 Oct;22(9):400-402. doi: 10.1016/j.micinf.2020.07.002. Epub 2020 Jul 9.
Abstract
In this commentary we argue that the hygiene hypothesis may apply to COVID-19 susceptibility and also that residence in low hygienic conditions acts to train innate immune defenses to minimize the severity of infection. We advocate that approaches, which elevate innate immune functions, should be used to minimize the consequences of COVID-19 infection at least until effective vaccines and antiviral therapies are developed.
摘要
在这篇评论中，我们认为卫生假说可能适用于 COVID-19 的易感性，并且居住在低卫生条件下也会训练先天免疫防御，以最大程度降低感染的严重程度。我们主张，应采用提高先天免疫功能的方法来减轻 COVID-19 感染的后果，至少在开发出有效疫苗和抗病毒疗法之前应如此。
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