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腹腔镜胆囊切除术在胰腺坏死微创管理现代方法中的严重和/或坏疽性胰腺炎中的作用。

The Role of Laparoscopic Cholecystectomy After Severe and/or Necrotic Pancreatitis in the Setting of Modern Minimally Invasive Management of Pancreatic Necrosis.

机构信息

From the Upper Gastrointestinal/Hepatobiliary and General Surgery Unit, Monash Health.

出版信息

Pancreas. 2020 Aug;49(7):935-940. doi: 10.1097/MPA.0000000000001601.

Abstract

OBJECTIVES

The trend toward minimally invasive procedures (MIP) in necrotizing pancreatitis is increasing. The optimal timing and technique of cholecystectomy in severe/necrotizing pancreatitis is unclear. This study aims to determine the role of laparoscopic cholecystectomy after severe/necrotizing pancreatitis in the context of MIP.

METHODS

Retrospective analysis of a prospective database was performed for consecutive patients after cholecystectomy for gallstone pancreatitis between January 2011 and January 2018 at Monash Health, Melbourne, Australia.

RESULTS

Three hundred fifty-five patients with gallstone pancreatitis underwent laparoscopic cholecystectomy with 2 conversions. Patients with severe pancreatitis were older (P = 0.002), with a more even sex distribution when compared with mild pancreatitis. Females predominated in the mild pancreatitis group.Patients with moderate/severe pancreatitis (P = 0.002) and necrosis (P > 0.001) were more likely to have delayed cholecystectomy compared with mild pancreatitis. There was no increase in biliary presentations while awaiting cholecystectomy. Length of stay for patients with severe/necrotizing pancreatitis (P = 0.001) was increased, surgical complications appeared similar.

CONCLUSIONS

Laparoscopic cholecystectomy can be performed safely and effectively for pancreatitis, irrespective of severity. The paradigm shift in the management of severe necrotizing pancreatitis away from open necrosectomy toward MIP can be extended to encompass laparoscopic cholecystectomy.

摘要

目的

在坏死性胰腺炎中,微创手术(MIP)的趋势正在增加。在重症/坏死性胰腺炎中,胆囊切除术的最佳时机和技术尚不清楚。本研究旨在确定在 MIP 背景下重症/坏死性胰腺炎后腹腔镜胆囊切除术的作用。

方法

对 2011 年 1 月至 2018 年 1 月期间在澳大利亚墨尔本蒙纳士健康中心因胆石性胰腺炎行腹腔镜胆囊切除术的连续患者的前瞻性数据库进行回顾性分析。

结果

355 例胆石性胰腺炎患者行腹腔镜胆囊切除术,其中 2 例转为开腹手术。重症胰腺炎患者年龄较大(P = 0.002),与轻症胰腺炎相比,性别分布更均匀。轻症胰腺炎组以女性为主。中度/重症胰腺炎(P = 0.002)和坏死(P > 0.001)患者与轻症胰腺炎相比,更有可能延迟胆囊切除术。在等待胆囊切除期间,胆道表现没有增加。重症/坏死性胰腺炎患者的住院时间延长(P = 0.001),手术并发症似乎相似。

结论

无论胰腺炎的严重程度如何,腹腔镜胆囊切除术都可以安全有效地进行。严重坏死性胰腺炎的管理模式从开放性坏死切除术向 MIP 的转变可以扩展到包括腹腔镜胆囊切除术。

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