Mood Disorders Psychopharmacology Unit, University Health Network, Toronto, Canada.
Mood Disorders Psychopharmacology Unit, University Health Network, Toronto, Canada; Department of Psychiatry, University of Toronto, Toronto, Canada; Department of Pharmacology, University of Toronto, Toronto, Canada.
J Affect Disord. 2020 Sep 1;274:602-609. doi: 10.1016/j.jad.2020.05.116. Epub 2020 May 25.
Major Depressive Disorder (MDD) is a common and debilitating mood disorder. Individuals with MDD are often misdiagnosed or diagnosed in an untimely manner, exacerbating existing functional impairments. Ecological momentary assessment (EMA) involves the repeated sampling of an individual's symptoms within their natural environment and has been demonstrated to assist in illness assessment and characterization. Capturing data in this way would set the stage for improved treatment outcomes and serve as a complementary resource in the management and treatment of depressive symptoms.
Online databases PubMed/MedLine and PsycINFO were searched using PRISMA guidelines and combinations of the following keywords: EMA, depression, smartphone app, diagnosing, symptoms, phone, app, ecological momentary assessment, momentary assessment, data mining, unobtrusive, passive data, GPS, sensor.
A total of nineteen original articles were identified using our search parameters and ten articles met the inclusion criteria for full-text review. Among the ten relevant studies, three studies evaluated feasibility, seven evaluated detection, and three evaluated treatment of MDD.
Limitations include that the design of all of the studies included in this review are non-randomized. It should be noted that most of the studies included were pilot studies and/or exploratory trials lacking a control group.
Available evidence suggests that the use of passive smartphone-based applications may lead to improved management of depressive symptoms. This review aids the creation of new EMA applications, highlights the potential of EMA usage in clinical settings and drug development, emphasizes the importance for regulation of applications in the mental health field, and provides insight into future directions.
重度抑郁症(MDD)是一种常见且使人虚弱的情绪障碍。患有 MDD 的个体经常被误诊或未能及时诊断,从而加重现有的功能障碍。生态瞬时评估(EMA)涉及在个体的自然环境中反复采样个体的症状,并已被证明有助于疾病评估和特征描述。以这种方式捕获数据将为改善治疗结果奠定基础,并成为管理和治疗抑郁症状的补充资源。
使用 PRISMA 指南和以下关键词的组合在在线数据库 PubMed/MedLine 和 PsycINFO 中进行搜索:EMA、抑郁、智能手机应用程序、诊断、症状、电话、应用程序、生态瞬时评估、瞬时评估、数据挖掘、不引人注目的、被动数据、GPS、传感器。
使用我们的搜索参数共确定了 19 篇原始文章,其中 10 篇文章符合全文审查的纳入标准。在这 10 项相关研究中,有 3 项研究评估了可行性,7 项研究评估了检测,3 项研究评估了 MDD 的治疗。
本综述中包含的所有研究的设计都不是随机的。应当注意的是,大多数纳入的研究都是缺乏对照组的试点研究和/或探索性试验。
现有证据表明,使用基于被动智能手机的应用程序可能有助于改善抑郁症状的管理。本综述有助于创建新的 EMA 应用程序,突出了 EMA 在临床环境和药物开发中的使用潜力,强调了对心理健康领域应用程序进行监管的重要性,并为未来的发展方向提供了思路。