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每一种药物都是药物;探索加纳农村社区层面的不当抗生素使用情况。

Every medicine is medicine; exploring inappropriate antibiotic use at the community level in rural Ghana.

机构信息

Kintampo Health Research Centre, Ghana Health Service, Kintampo, Bono East Region, Ghana.

Radboud University Medical Centre, Department of Medical Microbiology and Radboudumc Center for Infectious Diseases, Nijmegen, Netherlands.

出版信息

BMC Public Health. 2020 Jul 14;20(1):1103. doi: 10.1186/s12889-020-09204-4.

Abstract

BACKGROUND

Inappropriate antibiotic use is an important driver of antibiotic resistance. This study sought to explore inappropriate antibiotic use and confusing antibiotics with other medicines in Ghana using ethnomethodology research approach.

METHODS

This was an explorative study involving 15 in-depth interviews among health professionals and private dispensers and eight focus group discussions among 55 community members. Qualitative data were coded using Nvivo 12, thematically analysed and presented as narratives with quotes to support the findings.

RESULTS

Self-medication was common and antibiotics were used to treat specific diseases but respondents were not aware these were 'antibiotics'. Various antibiotics were used for indications that in principle do not require systemic antibiotics, like stomach ache and sores on the body. Antibiotics, in particular tetracycline and metronidazole, were poured into "akpeteshie" (local gin) to treat hernia and perceived stomach sores (stomach ulcer). These practices were copied/learnt from various sources like over-the-counter medicine sellers, family, friends, radio/television, drug peddlers, pharmacies and doctors. Medicines in capsules were referred to as 'topaye' or 'abombelt' in Twi (local dialect) and perceived to treat pain associated with diseases. Antibiotics in capsules were described with colours which appeared confusing as some capsules with different drugs in them have similar colours.

CONCLUSION

Inappropriate antibiotic use were influenced by general lack of knowledge on antibiotics and identification of antibiotics by colours of capsules which leads to confusion and could lead to inappropriate antibiotic use. There is the need for public health education on appropriate antibiotic use and standardization of appearance of antibiotics and other drugs to optimize use.

摘要

背景

抗生素的不恰当使用是抗生素耐药性的一个重要驱动因素。本研究采用民族方法论研究方法,旨在探索加纳抗生素使用不当和将抗生素与其他药物混淆的情况。

方法

这是一项探索性研究,涉及 15 名卫生专业人员和私人药剂师的深入访谈,以及 55 名社区成员的 8 个焦点小组讨论。使用 Nvivo 12 对定性数据进行编码,进行主题分析,并以叙述的形式呈现,引用引号来支持研究结果。

结果

自我医疗很常见,抗生素用于治疗特定疾病,但受访者不知道这些是“抗生素”。各种抗生素用于原则上不需要全身抗生素的适应症,如腹痛和身体上的疮。抗生素,特别是四环素和甲硝唑,被倒入“akpeteshie”(当地杜松子酒)中治疗疝气和被认为是胃部疮(胃溃疡)。这些做法是从各种来源复制/学习的,如非处方药卖家、家庭、朋友、广播/电视、药贩子、药店和医生。胶囊中的药物在 Twi(当地方言)中被称为“topaye”或“abombelt”,被认为可以治疗与疾病相关的疼痛。胶囊中的抗生素根据颜色进行描述,这让人感到困惑,因为一些含有不同药物的胶囊具有相似的颜色。

结论

抗生素使用不当的原因是普遍缺乏对抗生素的知识,以及通过胶囊的颜色来识别抗生素,这导致了混淆,并可能导致不恰当的抗生素使用。需要进行公众对抗生素合理使用的健康教育,并对抗生素和其他药物的外观进行标准化,以优化使用。

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