Liu Huhu, Song Yulan, Fan Xiao, Wang Chong, Lu Xiangyang, Tian Yun
College of Bioscience and Biotechnology, Hunan Agricultural University, Changsha, China.
Front Microbiol. 2021 Jan 5;11:608662. doi: 10.3389/fmicb.2020.608662. eCollection 2020.
The microbial fermentation process has been used as an alternative pathway to the production of value-added natural products. Of the microorganisms, , as an oleaginous platform, is able to produce fatty acid-derived biofuels and biochemicals. Nowadays, there are growing progresses on the production of value-added fatty acid-based bioproducts in . . However, there are fewer reviews performing the metabolic engineering strategies and summarizing the current production of fatty acid-based bioproducts in . To this end, we briefly provide the fatty acid metabolism, including fatty acid biosynthesis, transportation, and degradation. Then, we introduce the various metabolic engineering strategies for increasing bioproduct accumulation in . Further, the advanced progress in the production of fatty acid-based bioproducts by , including nutraceuticals, biofuels, and biochemicals, is summarized. This review will provide attractive thoughts for researchers working in the field of .
微生物发酵过程已被用作生产增值天然产物的替代途径。在微生物中,作为一个产油平台,能够生产脂肪酸衍生的生物燃料和生物化学品。如今,在[具体微生物名称]中生产增值脂肪酸基生物产品方面有了越来越多的进展。然而,较少有综述探讨[具体微生物名称]中的代谢工程策略并总结当前脂肪酸基生物产品的生产情况。为此,我们简要介绍脂肪酸代谢,包括脂肪酸生物合成、运输和降解。然后,我们介绍用于增加[具体微生物名称]中生物产品积累的各种代谢工程策略。此外,还总结了[具体微生物名称]生产脂肪酸基生物产品(包括营养保健品、生物燃料和生物化学品)方面的最新进展。本综述将为该领域的研究人员提供有吸引力的思路。