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H1和H2质粒的不相容性及表面排斥特性

Incompatibility and surface exclusion properties of H1 and H2 plasmids.

作者信息

Taylor D E, Grant R B

出版信息

J Bacteriol. 1977 Jul;131(1):174-8. doi: 10.1128/jb.131.1.174-178.1977.

Abstract

Plasmids of the H incompatibility group showed two types of surface exclusion and incompatibility interactions. Strong incompatibility and surface exclusion were evident between plasmids within the same subgroup, and recombination frequently occurred between these plasmids after antibiotic selection for the presence of two plasmids in the same cell. Weaker interactions were seen between plasmids of the different subgroups, H1 and H2, and recombination was not detected. Incompatibility between H1 and H2 plasmids led preferentially to the loss of the H1 plasmid, irrespective of the order of entry of the plasmids. These data are consistent with the hypothesis that incompatibility is negatively controlled.

摘要

H不相容性组的质粒表现出两种类型的表面排斥和不相容性相互作用。同一亚组内的质粒之间存在强烈的不相容性和表面排斥,在抗生素选择同一细胞中存在两种质粒后,这些质粒之间经常发生重组。在不同亚组H1和H2的质粒之间观察到较弱的相互作用,未检测到重组。H1和H2质粒之间的不相容性优先导致H1质粒的丢失,而与质粒进入的顺序无关。这些数据与不相容性受负调控的假设一致。

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