Life Sciences Institute, Guangxi Medical University, Nanning, China.
State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China.
Vector Borne Zoonotic Dis. 2020 Oct;20(10):755-762. doi: 10.1089/vbz.2019.2597. Epub 2020 Jul 15.
As one of the important tick-borne zoonotic pathogens, has both veterinary and public health significance. Here, we performed a survey of infection in the goats from a farm in Beijing, China, and found 44.6% (41/92) were infected with , and 22.8% (21/92) were infected with sp. This sp. bacterium was close to a recently emerging strain based on and gene phylogenetic analysis. As to further understand the characteristics of sp., we raised a couple of positive goats ( = 2) in the laboratory with tick-free settings. We observed inappetence, vomiting, high fever, and weakness of limbs in the goat's offspring ( = 3). In addition, the blood samples from all offspring were all positive of this spp. We did not see any intracellular morulae in neutrophils, monocytes, and erythrocytes, but we identified some in the platelets of the blood smears from the positive goats by light microscopy. We named it like and suggested it may infect platelets and be transmitted vertically through the placenta of goats. These findings deserve further evaluation.
作为重要的蜱传动物源性人畜共患病病原体之一，在中国，我们对来自北京某农场的山羊进行了调查，发现 44.6%（41/92）的山羊感染了 ，22.8%（21/92）的山羊感染了 sp. 这种 sp. 细菌与基于 和 基因系统发育分析的最近出现的菌株密切相关。为了进一步了解 sp. 的特征，我们在实验室中用无蜱的环境饲养了一对阳性山羊（ = 2）。我们观察到山羊的后代（ = 3）出现食欲不振、呕吐、高热和四肢无力的症状。此外，所有后代的血液样本均为 sp. 阳性。我们在中性粒细胞、单核细胞和红细胞中未观察到任何细胞内包涵体，但通过光学显微镜在阳性山羊的血涂片血小板中鉴定出一些包涵体。我们将其命名为类似物，并建议它可能感染血小板，并通过胎盘垂直传播给山羊。这些发现值得进一步评估。
