Research Group on Biotechnology and Bioprospecting Applied to Metabolism, Federal University of Grande Dourados, Dourados, Brazil.
Research Group on Biotechnology and Bioprospecting Applied to Metabolism, Federal University of Grande Dourados, Dourados, Brazil.
J Nutr Biochem. 2020 Nov;85:108428. doi: 10.1016/j.jnutbio.2020.108428. Epub 2020 May 26.
Polyphenols have demonstrated several potential biological activities, notably antitumoral activity dependent on immune function. In the present review, we describe studies that investigated antitumor immune responses influenced by polyphenols and the mechanisms by which polyphenols improve the immune response. We also discuss the limitations in related areas, especially unexplored areas of research, and next steps required to develop a therapeutic approach utilizing polyphenols in oncology.
多酚表现出多种潜在的生物活性，特别是依赖于免疫功能的抗肿瘤活性。在本综述中，我们描述了研究多酚影响抗肿瘤免疫反应以及多酚改善免疫反应的机制的研究。我们还讨论了相关领域的局限性，特别是研究中尚未涉及的领域，以及为开发利用多酚治疗肿瘤的方法所需采取的下一步措施。
