Unité de recherche Etudes Pharmaco-Immunologie (EPI), Université de La Réunion, CHU La Réunion site Félix Guyon, Allée des Topazes, CS11021, 97400 Saint Denis de La Réunion, France.
Faculté de Médecine, Université d'Antananarivo, Campus Universitaire Ambohitsaina, BP 375, Antananarivo 101, Madagascar.
Int J Mol Sci. 2020 Jul 15;21(14):4986. doi: 10.3390/ijms21144986.
Traditional remedies have been used for thousand years for the prevention and treatment of infectious diseases, particularly in developing countries. Of growing interest, the plant , known for its malarial properties, has been studied for its numerous biological activities including metabolic, anti-tumor, anti-microbial and immunomodulatory properties. is very rich in secondary metabolites such as monoterpenes, sesquiterpenes and phenolic compounds, of which the biological properties have been extensively studied. The purpose of this review is to gather and describe the data concerning the main chemical components produced by and to describe the state of the art about the biological activities reported for this plant and its compounds beyond malaria.
传统疗法已经被使用了数千年,用于预防和治疗传染病,特别是在发展中国家。越来越受到关注的是,这种植物以其抗疟疾特性而闻名,它的许多生物活性也得到了研究,包括代谢、抗肿瘤、抗微生物和免疫调节特性。它富含多种次生代谢产物,如单萜、倍半萜和酚类化合物,其中生物特性已经得到了广泛的研究。本文的目的是收集和描述由 产生的主要化学成分的数据,并描述除疟疾以外,关于这种植物及其化合物的生物活性的最新研究进展。