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马德里在 COVID-19 大流行期间对临产孕妇进行 SARS-CoV-2 普筛

Universal screening for SARS-CoV-2 before labor admission during Covid-19 pandemic in Madrid.

机构信息

Fetal Medicine Unit - Maternal and Child Health and Development Network (Red SAMID-RD12/0026/0016), Department of Obstetrics and Gynecology, Hospital Universitario 12 de Octubre, Instituto de Investigación Hospital 12 de Octubre (imas12), Universidad Complutense de Madrid, Madrid, Spain.

Department of Clinical Microbiology, Hospital Universitario 12 de Octubre, Instituto de Investigación Hospital 12 de Octubre (imas12), Universidad Complutense de Madrid, Madrid, Spain.

出版信息

J Perinat Med. 2020 Nov 26;48(9):981-984. doi: 10.1515/jpm-2020-0236.

Abstract

Objectives Asymptomatic women admitted to labor may act as silent spreaders of COVID-19. Therefore, universal screening at admission has been proposed. The objective of the study was to evaluate the performance of universal screening for SARS-CoV-2 using quantitative reverse transcription polymerase-chain-reaction (qRT-PCR) tests in women admitted to labor. Methods Observational retrospective study of a cohort of pregnant women admitted to labor and delivery between April 8 and May 2, 2020 in a large maternity in Madrid. SARS-CoV-2 screening with qRT-PCR from combined nasopharyngeal and oropharyngeal swabs was carried out systematically. Screening performance was described. Results We attended 212 deliveries. Nine cases with COVID-19 diagnosis before admission were excluded. In the remaining 203 women, seven referred COVID-19-related symptoms but only one had a positive qRT-PCR. Among the 194 asymptomatic women, only one case (0.5%) was positive. Conclusions The percentage of positive tests in asymptomatic women admitted to delivery was only 0.5% during the post-peak period.

摘要

目的

无症状的临产妇女可能是 COVID-19 的隐性传播者。因此,建议在入院时进行普遍筛查。本研究的目的是评估在临产妇女中使用定量逆转录聚合酶链反应(qRT-PCR)检测对 SARS-CoV-2 进行普遍筛查的性能。

方法

这是一项在马德里一家大型妇产科医院于 2020 年 4 月 8 日至 5 月 2 日期间对临产孕妇进行的观察性回顾性队列研究。对合并鼻咽和口咽拭子的 qRT-PCR 进行了系统性 SARS-CoV-2 筛查。描述了筛查性能。

结果

我们共参与了 212 次分娩。有 9 例在入院前已确诊为 COVID-19 的病例被排除。在其余的 203 名妇女中,有 7 名有 COVID-19 相关症状,但只有 1 名 qRT-PCR 阳性。在 194 名无症状的妇女中,只有 1 例(0.5%)呈阳性。

结论

在 COVID-19 疫情高峰期过后,入院分娩的无症状妇女中,只有 0.5% 的检测结果呈阳性。

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