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一例经聚合酶链反应确诊的新型冠状病毒肺炎患者合并右心室血栓和双侧深静脉血栓形成的病例报告

A Case Report of Polymerase Chain Reaction-Confirmed COVID-19 in a Patient With Right Ventricular Thrombus and Bilateral Deep Vein Thrombosis.

作者信息

Elkattawy Sherif, Younes Islam, Noori Muhammad Atif Masood

机构信息

Internal Medicine, Rutgers New Jersey Medical School/Trinitas Regional Medical Center, Elizabeth, USA.

Internal Medicine, Dow Medical College, Karachi, PAK.

出版信息

Cureus. 2020 Jun 15;12(6):e8633. doi: 10.7759/cureus.8633.

Abstract

The new coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), that causes the highly contagious coronavirus disease 2019 (COVID-19) has led to an unprecedented global health crisis. Infected patients have been shown to trigger a heightened inflammatory response, increasing thrombotic risk. We report the case of a polymerase chain reaction (PCR)-confirmed COVID-19 in a Hispanic male with no past medical history who presented to the ED with upper respiratory tract symptoms including shortness of breath and cough, requiring continuous positive airway pressure(CPAP) therapy. He was found to have a right ventricular thrombus (RVT) and bilateral deep vein thrombosis (DVT) on the day of admission, which were detected on transthoracic echocardiogram and duplex venous ultrasound, respectively. The patient was started on therapeutic enoxaparin sodium, which led to an improvement in oxygenation, and he was eventually downgraded to the medical floors for further management.

摘要

导致具有高度传染性的2019冠状病毒病(COVID-19)的新型冠状病毒,即严重急性呼吸综合征冠状病毒2(SARS-CoV-2),已引发了一场前所未有的全球健康危机。已证明感染患者会引发更强的炎症反应,增加血栓形成风险。我们报告了一例经聚合酶链反应(PCR)确诊的COVID-19病例,患者为一名无既往病史的西班牙裔男性,因出现包括呼吸急促和咳嗽在内的上呼吸道症状前往急诊科就诊,需要持续气道正压通气(CPAP)治疗。入院当天,经胸超声心动图和双功静脉超声检查分别发现他有右心室血栓(RVT)和双侧深静脉血栓形成(DVT)。患者开始接受治疗剂量的依诺肝素钠治疗,这使氧合情况得到改善,最终他被转至普通病房进行进一步治疗。

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