Department of Pharmacy, College of Medicine and Health Science, Bahir Dar University, Bahir Dar, Ethiopia.
School of Pharmacy, College of Health Science, Mekelle University, Mekelle, Ethiopia.
Biomed Res Int. 2020 Jun 27;2020:3809157. doi: 10.1155/2020/3809157. eCollection 2020.
Irrational prescribing is a major cause for irrational drug use. Bad prescribing habits lead to ineffective and unsafe treatment, exacerbation or prolongation of illness, distress and harm to the patient, and higher costs. Incidence of irrational prescribing practice cannot be reduced without a critical intervention by assessing the causes.
The objective of this study was to assess drug prescription pattern, using WHO prescribing indicators, in OPD at Mekelle General Hospital (MGH) . The study was conducted at Mekelle General Hospital (MGH), Mekelle, Northern Ethiopia, from December 2016 to April 2017. A descriptive cross-sectional, retrospective hospital-based study design was used to assess prescriptions at OPD in MGH from 01 January to 31 December 2016. A systematic random sampling technique was used to select prescriptions at the time of data collection.
384 prescriptions were analyzed. 751 medications were prescribed from which 679 (90.4%) were with their generic name, 225 (58.6%) prescriptions contained antibiotics, 162 (42.2%) prescriptions were encountered with injection, and 648 (86.3%) encountered from the hospital list of medicine.
In general, average number of drugs per encounter, generic prescribing, and the use of EDL/formulary of the hospital to prescribe drugs reviewed in this study were totally out of the recommended values and hence inappropriate. The study also revealed overprescribing of both antibiotics and injections.
不合理处方是不合理用药的主要原因。不良的处方习惯会导致治疗无效和不安全,加重或延长疾病,给患者带来痛苦和伤害,并增加成本。如果不通过评估原因来进行关键干预,不合理处方的发生率就无法降低。
本研究旨在评估在梅开勒综合医院(MGH)的门诊(OPD)中使用世界卫生组织(WHO)处方指标的药物处方模式。该研究于 2016 年 12 月至 2017 年 4 月在埃塞俄比亚北部的梅开勒综合医院(MGH)进行。采用描述性横断面、回顾性医院基础研究设计,评估 2016 年 1 月 1 日至 12 月 31 日期间在 MGH 的 OPD 中的处方。在数据收集时使用系统随机抽样技术选择处方。
分析了 384 张处方。共开具了 751 种药物,其中 679 种(90.4%)为通用名药物,225 种(58.6%)处方含有抗生素,162 种(42.2%)处方为注射剂,648 种(86.3%)处方来自医院药品清单。
总的来说,在本次研究中审查的每次就诊的平均药物数量、通用名处方和使用 EDL/医院处方集的情况完全超出了推荐值,因此是不合适的。该研究还显示出抗生素和注射剂的过度处方。