Department of Preventive Medicine, Fujian Provincial Key Laboratory of Environment Factors and Cancer, Key Laboratory of Environment and Health, School of Public Health, Fujian Medical University, Fuzhou, China.
Fuzhou Center for Disease Control and Prevention, Fuzhou, China.
BMC Public Health. 2020 Jul 20;20(1):1131. doi: 10.1186/s12889-020-08915-y.
Previous studies have suggested that there is an association between air pollutants and circulatory and respiratory diseases; however, relatively few have analyzed the association between air pollutants and outpatient visits based on the mortality, hospitalization rates, etc., especially in areas with relatively good air quality. Therefore, we conducted this study to research the association between air pollutants and outpatient visits in Fuzhou, China.
We used a generalized linear Poisson model to study the association between air pollution and outpatient visits for respiratory and circulatory diseases from 2016 to 2018 in Fuzhou, China.
In the single pollutant model, nitrogen dioxide (NO) had a significant effect. For lag day 0 to lag day 5, the effect decreased with every 10 μg/L increase in NO. The daily maximum 8-h mean ozone (O-8h) and upper respiratory outpatient visits were positively associated during the cold period [lag2, excess risk (ER) (95% confidence interval (CI)): 1.68% (0.44-2.94%)], while O-8h and respiratory disease were positively associated during the warm period [lag5, ER (95% CI): 1.10% (0.11-2.10%) and lag4, ER (95% CI): 1.02% (0.032-2.02%)]. Similarly, particulate matter (PM) with an average aerodynamic diameter of less than 10 μm (PM) and lower respiratory diseases were positively associated during the warm period [lag0, ER (95% CI): 1.68% (0.44-2.94%)]. When the concentration of O-8h was higher than 100 μg/L, there was a positive effect on circulatory [lag5, ER (95% CI): 2.83% (0.65-5.06%)], respiratory [lag5, ER (95% CI): 2.47% (0.85-4.11%)] and upper respiratory [lag5, ER (95% CI): 3.06% (1.38-4.77%)] outpatient visits. The variation in O-8h changed slightly when we adjusted for other air pollutants, and after adjusting for O-8h, the ERs of the other air pollutants changed slightly. After adjusting for PM with an average aerodynamic diameter of less than 2.5 μm (PM), the ERs of the other air pollutants increased, and after adjusting for NO, the ER of PM decreased.
Exposure to ambient NO, O, PM and PM was associated with an increase in respiratory and circulatory system-related outpatient visits in Fuzhou, China.
先前的研究表明，空气污染物与循环和呼吸系统疾病之间存在关联；然而，很少有研究根据死亡率、住院率等分析空气污染物与门诊就诊之间的关系，特别是在空气质量相对较好的地区。因此，我们进行了这项研究，以研究中国福州空气污染物与门诊就诊之间的关系。
我们使用广义线性泊松模型研究了 2016 年至 2018 年期间福州空气污染物与呼吸和循环系统疾病门诊就诊之间的关系。
在单污染物模型中，二氧化氮（NO）有显著影响。对于滞后 0 至 5 天，NO 每增加 10μg/L，效应就会降低。寒冷期内，日最大 8 小时平均臭氧（O-8h）与上呼吸道门诊就诊呈正相关[滞后 2 天，超额风险（ER）（95%置信区间（CI））：1.68%（0.44-2.94%）]，而温暖期内 O-8h 与呼吸系统疾病呈正相关[滞后 5 天，ER（95%CI）：1.10%（0.11-2.10%）和滞后 4 天，ER（95%CI）：1.02%（0.032-2.02%）]。同样，平均空气动力学直径小于 10μm 的颗粒物（PM）与温暖期的下呼吸道疾病呈正相关[滞后 0 天，ER（95%CI）：1.68%（0.44-2.94%）]。当 O-8h 浓度高于 100μg/L 时，对循环系统[滞后 5 天，ER（95%CI）：2.83%（0.65-5.06%）]、呼吸系统[滞后 5 天，ER（95%CI）：2.47%（0.85-4.11%）]和上呼吸道[滞后 5 天，ER（95%CI）：3.06%（1.38-4.77%）]的门诊就诊有正向影响。调整其他空气污染物后，O-8h 的变化略有变化，调整 O-8h 后，其他空气污染物的 ER 略有变化。调整平均空气动力学直径小于 2.5μm 的颗粒物（PM）后，其他空气污染物的 ER 增加，调整 NO 后，PM 的 ER 降低。
在中国福州，暴露于环境中的 NO、O、PM 和 PM 与呼吸系统和循环系统相关疾病的门诊就诊率增加有关。
