Usul Eren, Şan İshak, Bekgöz Burak, Şahin Ali
Sincan Dr Nafiz Körez State Hospital, Emergency Service, Ankara, Turkey.
Department of Emergency Medicine, University of Health Sciences, Ankara City Hospital, Ankara, Turkey.
Biomark Med. 2020 Sep;14(13):1207-1215. doi: 10.2217/bmm-2020-0317. Epub 2020 Jul 21.
In this study, the roles of biomarkers from a peripheral blood sample in the diagnosis of COVID-19 patients who have visited the emergency room have been evaluated. Peripheral blood parameters, systemic inflammatory index (SII), neutrophil lymphocyte ratio (NLR) and platelet lymphocyte ratio were compared in patients with and without confirmed COVID-19 infection. Comparisons made according to real-time PCR test results revealed that while no statistically significant difference was observed between test groups (negative-positive) regarding lymphocyte and platelet lymphocyte ratio values (p > 0.05), a statistically significant difference (p < 0.05) was found between the test groups regarding platelet, hemoglobin, leukocyte, neutrophil, NLR and SII values. Leukocyte, neutrophil, platelet count, NLR and SII values can be used in the diagnosis of COVID-19.
在本研究中，已对来自外周血样本的生物标志物在诊断前往急诊室的新冠肺炎患者中的作用进行了评估。对确诊和未确诊新冠肺炎感染的患者的外周血参数、全身炎症指数（SII）、中性粒细胞淋巴细胞比值（NLR）和血小板淋巴细胞比值进行了比较。根据实时聚合酶链反应检测结果进行的比较显示，在淋巴细胞和血小板淋巴细胞比值方面，测试组（阴性-阳性）之间未观察到统计学上的显著差异（p>0.05），但在血小板、血红蛋白、白细胞、中性粒细胞、NLR和SII值方面，测试组之间存在统计学上的显著差异（p<0.05）。白细胞、中性粒细胞、血小板计数、NLR和SII值可用于新冠肺炎的诊断。
