Eyiol Azmi, Ertekin Birsen
Department of Cardiology, University of Health Sciences, Beyhekim Training & Research Hospital, Konya, Turkey.
Department of Emergency, University of Health Sciences, Beyhekim Training & Research Hospital, Konya, Turkey.
Biomark Med. 2024;18(7):311-320. doi: 10.2217/bmm-2023-0460. Epub 2024 Apr 22.
The authors investigated the association of red blood cell distribution width to albumin ratio (RAR) with prognosis and severity in acute ischemic stroke (AIS). One hundred twenty-seven patients with AIS were prospectively analyzed. The NIH Stroke Scale was used to determine stroke severity. RAR was compared between severe and nonsevere patients. RAR was significantly higher in severe compared with nonsevere patients (p < 0.001). According to receiver operating characteristic analysis, RAR alone predicted mortality better than red blood cell distribution width and albumin (area under the curve: 0.933, 0.911, 0.870, respectively). Additionally, RAR was significantly correlated with NIH Stroke Scale score (p < 0.001). High RAR measured at presentation is a feasible index for prognosis and severity stratification in AIS.
作者研究了急性缺血性卒中（AIS）患者红细胞分布宽度与白蛋白比值（RAR）与预后及严重程度的相关性。对127例AIS患者进行了前瞻性分析。采用美国国立卫生研究院卒中量表（NIHSS）确定卒中严重程度。比较了重度和非重度患者的RAR。重度患者的RAR显著高于非重度患者（p<0.001）。根据受试者工作特征分析，单独的RAR预测死亡率的能力优于红细胞分布宽度和白蛋白（曲线下面积分别为：0.933、0.911、0.870）。此外，RAR与NIHSS评分显著相关（p<0.001）。入院时测得的高RAR是AIS患者预后和严重程度分层的可行指标。
