Li Adrienne L K, Zajichek Alex, Kattan Michael W, Ji Xinge Kathy, Lo Katherine A, Lee Patricia E
Division of Urogynecology, Department of Obstetrics and Gynecology, Sunnybrook Health Sciences Centre, Toronto, ON.
Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH.
J Obstet Gynaecol Can. 2020 Oct;42(10):1203-1210. doi: 10.1016/j.jogc.2020.03.021. Epub 2020 Apr 27.
To develop a nomogram that determines an individual's risk of postoperative urinary retention (POUR) following pelvic floor reconstructive surgery.
We performed a retrospective chart review of women who underwent reconstructive surgery for pelvic organ prolapse and/or stress urinary incontinence. Short-term POUR was defined as failure of the trial of void (post-void residual >150 mL with a void of >200 mL) on postoperative day one or the need for re-catheterization in the first 2 postoperative days. Potential pre- and intraoperative risk factors for POUR were compared between patients with and without POUR. Multivariate binary logistic regression analysis with best-subsets variable selection was used to create a predictive nomogram.
Most patients (275 of 332) had concomitant or combined procedures. The overall incidence of POUR was 31% (103 of 332 patients). The risk of POUR was higher for patients with high-grade anterior prolapse and those who had undergone anterior vaginal repair, vaginal hysterectomy, or a laparoscopic sling procedure. Patients who did not experience POUR tended to have fewer co-morbidities and were more likely to have undergone laparoscopic colposacropexy. Risk factors for POUR in the nomogram were diabetes, multiple medical co-morbidities, laparoscopic sling procedure, anterior vaginal repair, laparoscopic colposacropexy, and vaginal hysterectomy. The nomogram allows clinicians to calculate a patient's risk of POUR (range <10% to >80%).
While the predictive nomogram in this study was developed using a single surgeon's case series and may not be generalizable to all surgeons, it demonstrates that the risk of POUR may be predicted based on clinical characteristics and the type of surgery performed. This kind of prediction model could help guide clinicians in preoperative patient counseling.
开发一种列线图,以确定个体在盆底重建手术后发生术后尿潴留(POUR)的风险。
我们对接受盆腔器官脱垂和/或压力性尿失禁重建手术的女性进行了回顾性病历审查。短期POUR定义为术后第一天试排尿失败(排尿后残余尿量>150 mL且尿量>200 mL)或术后前两天内需要再次导尿。比较发生POUR和未发生POUR的患者之间潜在的术前和术中POUR风险因素。采用最佳子集变量选择的多变量二元逻辑回归分析来创建预测列线图。
大多数患者(332例中的275例)进行了联合或合并手术。POUR的总体发生率为31%(332例患者中的103例)。重度前壁脱垂患者以及接受过阴道前壁修补术、阴道子宫切除术或腹腔镜吊带手术的患者发生POUR的风险更高。未发生POUR的患者往往合并症较少,且更有可能接受腹腔镜阴道骶骨固定术。列线图中POUR的风险因素包括糖尿病、多种合并症、腹腔镜吊带手术、阴道前壁修补术、腹腔镜阴道骶骨固定术和阴道子宫切除术。该列线图使临床医生能够计算患者发生POUR的风险(范围<10%至>80%)。
虽然本研究中的预测列线图是使用单一外科医生的病例系列开发的,可能不适用于所有外科医生,但它表明POUR的风险可以根据临床特征和所进行的手术类型进行预测。这种预测模型可以帮助指导临床医生在术前对患者进行咨询。