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[角膜曲率计指数的反推计算——白内障手术中哪个值才是正确的?]

[Back-calculation of the keratometer index-Which value would have been correct in cataract surgery?].

作者信息

Langenbucher Achim, Eberwein Philipp, Fabian Ekkehard, Szentmáry Nóra, Weisensee Johannes

机构信息

Institut für Experimentelle Ophthalmologie, Universität des Saarlandes, Kirrberger Str., Gebäude 22, 66421, Homburg, Deutschland.

Augencentrum Rosenheim, Bahnhofstr. 12, 83022, Rosenheim, Deutschland.

出版信息

Ophthalmologe. 2021 Apr;118(4):356-366. doi: 10.1007/s00347-020-01182-7.

Abstract

BACKGROUND AND PURPOSE

In the clinical routine the conversion of corneal radii into corneal refractive power using a keratometer index is rarely discussed. The purpose of this study was to back-calculate the keratometer index in pseudophakic eyes based on the refractive power of the lens, biometric measurements and refraction, and to compare it to clinically established values.

PATIENTS AND METHODS

In this retrospective case series 99 eyes of 99 patients without pathological alterations, previous diseases, comorbidities or history of ocular surgery apart from the uneventful cataract surgery were enrolled. In all eyes a CT Asphina 409M(P) (Carl-Zeiss Meditec, Berlin, Germany) had been implanted by two surgeons (EF and PE). For calculation we used shape and power data of the intraocular lens and data from optical biometry (axial length, pseudophakic anterior chamber depth, lens thickness, corneal radius; IOLMaster 700, Carl-Zeiss Meditec, Jena, Germany). The refraction was derived manually with a trial frame (measurement distance 5 m) and autorefractometry (iProfiler, Carl-Zeiss, Jena, Germany). For this three model eyes were used: a thin lens with the nominal refractive power positioned in the equatorial plane (model A) or in the secondary principal plane of the thick lens (model B) as well as a model considering the intraocular lens as a thick lens located at its measured position (model C).

RESULTS

Back-calculation of the keratometer index using vergence formulas resulted in a keratometer index based on subjective refraction measurements considering lane distance correction of 1.3307 ± 0.0026/1.3312 ± 0.0026/1.332 ± 0.0027 for model A/model B/model C, respectively. Based on objective refraction measurements (autorefraction calibrated to infinity object distances) resulted in a keratometer index of 1.3301 ± 0.0021/1.3306 ± 0.0021/1.3315 ± 0.0021, for model A/model B/model C, respectively. The keratometer index did not show any trend in linear regression for axial length or corneal radius for any of the three models or for any refraction method.

CONCLUSION

The keratometer index derived from back-calculation matched with the Zeiss index (1.332) but was much lower compared to other established indexes, e.g. the Javal index (1.3375). The missing trend for axial length or corneal radius implies that simple vergence formulas for intraocular lens refractive power calculation without correction terms or fudge factors perform best with a keratometer index slightly below 1.332, if the biometrically measured position of the intraocular lens is used as the effective lens position.

摘要

背景与目的

在临床实践中,很少讨论使用角膜曲率计指数将角膜半径转换为角膜屈光力。本研究的目的是根据晶状体的屈光力、生物测量数据和验光结果,对人工晶状体眼的角膜曲率计指数进行反算,并将其与临床确定的值进行比较。

患者与方法

在这个回顾性病例系列中,纳入了99例患者的99只眼,这些患者除了白内障手术顺利外,没有病理改变、既往疾病、合并症或眼部手术史。所有眼睛均由两位外科医生(EF和PE)植入了CT Asphina 409M(P)(德国柏林卡尔蔡司医疗技术公司)。为了进行计算,我们使用了人工晶状体的形状和屈光力数据以及光学生物测量数据(眼轴长度、人工晶状体眼的前房深度、晶状体厚度、角膜半径;德国耶拿卡尔蔡司医疗技术公司的IOLMaster 700)。验光采用试镜架手动测量(测量距离5米)和自动验光仪(德国耶拿卡尔蔡司公司的iProfiler)。为此使用了三种模型眼:一种是标称屈光力位于赤道平面的薄透镜(模型A)或厚透镜的第二主平面(模型B),以及一种将人工晶状体视为位于其测量位置的厚透镜的模型(模型C)。

结果

使用折射公式对角膜曲率计指数进行反算,基于考虑了物距校正的主观验光测量结果,模型A/模型B/模型C得到的角膜曲率计指数分别为1.3307±0.0026/1.3312±0.0026/1.332±0.0027。基于客观验光测量结果(自动验光校准至无穷远物距),模型A/模型B/模型C得到的角膜曲率计指数分别为1.3301±0.0021/1.3306±0.0021/1.3315±0.0021。对于三种模型中的任何一种或任何验光方法,角膜曲率计指数在眼轴长度或角膜半径的线性回归中均未显示出任何趋势。

结论

反算得出的角膜曲率计指数与蔡司指数(1.332)相符,但与其他既定指数相比要低得多,例如贾瓦尔指数(1.3375)。眼轴长度或角膜半径缺乏趋势意味着,如果将人工晶状体的生物测量位置用作有效晶状体位置,那么在不使用校正项或修正因子的情况下,用于计算人工晶状体屈光力的简单折射公式在角膜曲率计指数略低于1.332时表现最佳。

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