Department of Ophthalmology, Faculty of Medicine, Tanta University, Tanta, Egypt.
Eur J Ophthalmol. 2021 Jul;31(4):1762-1770. doi: 10.1177/1120672120945664. Epub 2020 Jul 22.
To evaluate changes in corneal biomechanics after LASIK and F-SMILE.
Elite Eye Center, Tanta, Egypt.
Prospective, randomized, unmasked, interventional comparative case series.
A total of 60 eyes were equally divided into two groups; group A: received LASIK and group B: received F-SMILE. Pentacam and CorVis ST parameters were compared before and 6 months after procedures. ⩽ 0.05 was used for significance of results.
bIOP decreased by 0.762 ± 1.211 mmHg in group A ( = 0.092), and by 2.52 ± 1.389 mmHg in group B ( < 0.001) and the difference between groups became significant ( = 0.001). A1 increased significantly in group A only ( = 0.036); while A2 decreased insignificantly in both groups. DAR increased significantly in both groups ( < 0.001, = 0.022), but the difference between groups remained insignificant ( = 0.461). IR increased significantly in group A only ( < 0.001) and the difference between groups became significant ( = 0.026). ARTH decreased in both groups ( = 0.245, = 0.695) and the difference remained insignificant ( = 0.928). SP-A1 decreased in group A by 8.89 ± 1.38 mmHg/mm ( = 0.637), and by 32.6 ± 4.39 mmHg/mm in group B ( < 0.001) and the postoperative difference between groups was significant ( = 0.013). CBI increased significantly in group A ( < 0.001), but insignificantly in group B ( = 0.098) and postoperative difference between groups was highly significant ( < 0.001). A significant correlation was found between change in CCT and corresponding changes in DAR, IR, and ARTH after surgery in both groups.
The significant differences between groups postoperatively as regards bIOP ( = 0.001), IR ( = 0.026), SP-A1 ( = 0.013), and CBI ( < 0.001) indicate stiffer corneas after F-SMILE and suggest less influence on corneal biomechanics than LASIK.
评估 LASIK 和 F-SMILE 术后角膜生物力学的变化。
埃及坦塔精英眼科中心。
前瞻性、随机、非盲、干预性病例对照系列研究。
共有 60 只眼平均分为两组；A 组：接受 LASIK，B 组：接受 F-SMILE。比较术前和术后 6 个月 Pentacam 和 CorVis ST 参数。结果以 P ⩽ 0.05 为有统计学意义。
A 组 bIOP 降低 0.762 ± 1.211 mmHg（= 0.092），B 组降低 2.52 ± 1.389 mmHg（< 0.001），两组间差异有统计学意义（= 0.001）。A 组仅 A1 显著增加（= 0.036）；两组 A2 均无显著变化。两组 DAR 均显著增加（均< 0.001，= 0.022），但两组间差异无统计学意义（= 0.461）。A 组仅 IR 显著增加（< 0.001），两组间差异有统计学意义（= 0.026）。两组 ARTH 均降低（= 0.245，= 0.695），差异无统计学意义（= 0.928）。A 组 SP-A1 降低 8.89 ± 1.38 mmHg/mm（= 0.637），B 组降低 32.6 ± 4.39 mmHg/mm（< 0.001），术后两组间差异有统计学意义（= 0.013）。A 组 CBI 显著增加（< 0.001），B 组无显著增加（= 0.098），两组间术后差异有高度统计学意义（< 0.001）。两组术后 CCT 变化与 DAR、IR 和 ARTH 相应变化呈显著相关性。
术后两组间 bIOP（= 0.001）、IR（= 0.026）、SP-A1（= 0.013）和 CBI（< 0.001）差异有统计学意义，表明 F-SMILE 后角膜硬度增加，对角膜生物力学的影响小于 LASIK。
