From the Department of Orthopaedic Sports Surgery, Allegheny General Hospital, Pittsburgh, PA (Dr. Akhavan, Dr. Martinkovich, and Dr. DeMeo), and the Department of Orthopaedic Surgery, Illinois Valley Community Hospital, Peru, IL (Dr. Kasik).
J Am Acad Orthop Surg. 2020 Oct 15;28(20):e888-e899. doi: 10.5435/JAAOS-D-20-00142.
Bone marrow edema (BME) is a descriptive term used to describe high-signal intensity changes detected on magnetic resonance fluid-sensitive sequences that could be attributed to a number of underlying pathologies. Regardless of the cause, physiologic remodeling of the subchondral bone can be limited because of ongoing joint forces, increased focalization of stress, and reduced healing capacity of the subchondral bone. BME is a known prognostic factor associated with pain, dysfunction, and progressive cartilage damage. This review summarizes the current known causes of BMEs, theories related to histopathological changes, and current treatment options including novel biologic surgical options.
骨髓水肿（BME）是一个描述性术语，用于描述在磁共振液体敏感序列上检测到的高信号强度变化，这些变化可能归因于许多潜在的病理学。无论原因如何，由于持续的关节力、应力的集中化以及软骨下骨的愈合能力降低，软骨下骨的生理性重塑可能会受到限制。BME 是与疼痛、功能障碍和进行性软骨损伤相关的已知预后因素。本综述总结了目前已知的 BME 原因、与组织病理学变化相关的理论以及包括新型生物手术选择在内的当前治疗选择。
