Boddapati Venkat, Lee Nathan J, Mathew Justin, Vulapalli Meghana M, Lombardi Joseph M, Dyrszka Marc D, Sardar Zeeshan M, Lehman Ronald A, Riew K Daniel
The Spine Hospital, New York-Presbyterian/Columbia University Irving Medical Center, New York, NY, USA.
Global Spine J. 2021 Oct;11(8):1183-1189. doi: 10.1177/2192568220941453. Epub 2020 Jul 24.
Retrospective cohort study.
Although cervical disc arthroplasty (CDA) has become a well-established and effective treatment for symptomatic cervical degeneration, many patients with multilevel disease are not good candidates for CDA at all levels. For such patients, hybrid surgery (HS)-a combination of adjacent anterior cervical discectomy and fusion (ACDF) and CDA-may be more appropriate. Given the novelty of HS and the relative dearth of studies adequately assessing short-term perioperative complications, this current study sought to assess the short-term morbidity profile of HS, differences in operative duration, length of stay (LOS), and readmission and reoperation rates and reasons relative to a 2-level ACDF cohort.
All patients who underwent HS and 2-level ACDF were identified between 2011 and 2018 using a large, prospectively collected registry. Baseline patient characteristics and postoperative complications were compared using bivariate and/or multivariate analysis.
A total of 390 patients undergoing HS were identified. Two-level procedures were the most common (74.9%). Patients undergoing HS were more likely to be younger, male, and have fewer comorbidities. There were no differences between HS and 2-level ACDF in rates of any postoperative complication, transfusion, readmissions, and operative duration. However, HS had a decreased LOS (0.5 days), relative to a 2-level ACDF. HS patients had low rates of reoperation (1.28%) with 1 case for hematoma evacuation and another for revision CDA.
This study represents one of the largest cohorts of patients undergoing HS reported to date. Patients undergoing HS are not at increased risk of perioperative complications relative to a 2-level ACDF and may benefit from shorter LOS.
回顾性队列研究。
尽管颈椎间盘置换术(CDA)已成为治疗有症状颈椎退变的一种成熟且有效的方法,但许多患有多节段疾病的患者并非所有节段都适合进行CDA。对于这类患者,混合手术(HS)——相邻节段的颈椎前路椎间盘切除融合术(ACDF)与CDA的联合——可能更为合适。鉴于HS的新颖性以及充分评估短期围手术期并发症的研究相对较少,本研究旨在评估HS的短期发病情况、手术时间、住院时间(LOS)、再入院率和再次手术率的差异以及与双节段ACDF队列相比的相关原因。
使用一个大型的前瞻性收集的登记系统,确定2011年至2018年间所有接受HS和双节段ACDF的患者。使用双变量和/或多变量分析比较患者的基线特征和术后并发症。
共确定390例接受HS的患者。双节段手术最为常见(74.9%)。接受HS的患者更可能较年轻、为男性且合并症较少。HS和双节段ACDF在任何术后并发症、输血、再入院率和手术时间方面均无差异。然而,相对于双节段ACDF,HS的住院时间缩短了(0.5天)。HS患者的再次手术率较低(1.28%),其中1例为血肿清除,另1例为CDA翻修。
本研究是迄今为止报道的接受HS患者的最大队列研究之一。与双节段ACDF相比,接受HS的患者围手术期并发症风险并未增加,且可能从较短的住院时间中获益。