Shields Carol L, Kim Min, Lally Sara E, Chévez-Barrios Patricia, Shields Jerry A
Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA, USA.
Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston TX, USA.
Indian J Ophthalmol. 2020 Aug;68(8):1699-1701. doi: 10.4103/ijo.IJO_27_20.
We report a new observation of conjunctival intraepithelial neoplasia (CIN) in a young man following years of electronic cigarette use. A 22-year-old man with a 5-year electronic cigarette use (vaping) developed painless unilateral blurred vision in the right eye from mild superficial corneal opacification, unresponsive to topical antiviral therapy. Corneal scraping documented no infectious etiology. The abnormality persisted for 1 year and superficial keratectomy revealed high-grade CIN with enlarged pleomorphic and dyskeratotic cells. Interferon-alpha-2b was instituted. In this case, chronic exposure to electronic cigarette vapors (vaping) could have been associated with CIN in this young patient.
我们报告了一名年轻男子在多年使用电子烟后发生结膜上皮内瘤变（CIN）的新观察结果。一名22岁有5年电子烟使用史（吸电子烟）的男子，因右眼轻度浅表角膜混浊出现无痛性单侧视力模糊，局部抗病毒治疗无效。角膜刮片检查未发现感染病因。这种异常持续了1年，浅表角膜切除术显示为高级别CIN，伴有细胞增大、多形性和角化不良。开始使用α-2b干扰素治疗。在该病例中，长期接触电子烟烟雾（吸电子烟）可能与这位年轻患者的CIN有关。
