Department of Stem Cell and Regenerative Biology, Harvard University, 7 Divinity Avenue, Cambridge, MA, 02138, USA.
Burrell College of Osteopathic Medicine, 3501 Arrowhead Dr, Las Cruces, NM, 88003, USA.
Int Ophthalmol. 2021 Aug;41(8):2925-2932. doi: 10.1007/s10792-021-01842-w. Epub 2021 Apr 16.
Vaping, or the use of electronic cigarettes, was initially introduced as a step toward smoking cessation, but has become an increasingly popular option for smokers. Though advertised as safer than conventional cigarettes, these devices have been found to contain carcinogenic chemicals, air pollutants, and heavy metals. The purpose of this article is to shed light on the known effects of vaping on the ocular setting and raise the discussion about additional potential effects that may call for further investigation.
A comprehensive literature search was conducted for publications pertaining to the effects of vaping on the eye. Relevant studies and findings were summarized in this article.
It was found that aldehydes and free radicals present in electronic cigarettes may induce a disturbance in tear film stability, and vape flavorings may damage the lipid layer through peroxidation. Corneal staining has been shown to appear following exposure to e-cigarette vapor, with nicotine and acrolein potentially inducing an inflammatory response in corneal epithelial cells. In addition, nicotine has been shown to induce nystagmus, exert vasoconstrictive effects on ocular blood flow, and may interfere with retinal light-adapted vision. Vape-related explosions, though unpredictable, may also result in decreased visual acuity along with long-term ocular trauma.
Research discussing both the short-term and long-term effects of vaping on the eye is limited. However, the potential harms of substances such as nicotine and aldehydes warrant additional investigation and increased education about the detriment that electronic cigarettes may inflict on sensitive organs.
最初,电子烟的使用(即所谓的“ vaping”)被作为一种戒烟手段而引入,但它已成为吸烟者越来越受欢迎的选择。尽管这些设备被宣传为比传统香烟更安全,但已发现它们含有致癌化学物质、空气污染物和重金属。本文旨在阐明 vaping 对眼部的已知影响,并提出关于其他可能需要进一步研究的潜在影响的讨论。
对有关电子烟对眼睛影响的文献进行了全面的文献检索。本文总结了相关的研究和发现。
研究发现,电子烟中存在的醛类和自由基可能会引起泪膜稳定性紊乱,而电子烟调味剂可能会通过过氧化作用破坏脂质层。暴露于电子烟蒸汽后会出现角膜染色,尼古丁和丙烯醛可能会引起角膜上皮细胞的炎症反应。此外,尼古丁已被证明会引起眼球震颤,对眼部血流产生血管收缩作用,并可能干扰视网膜的光适应视力。与电子烟相关的爆炸虽然不可预测,但也可能导致视力下降以及长期眼部创伤。
目前关于 vaping 对眼睛的短期和长期影响的研究有限。然而,尼古丁和醛类等物质的潜在危害需要进一步研究,并加强对电子烟可能对敏感器官造成的危害的教育。