United States Department of Agriculture, Agricultural Research Service, Beltsville Agricultural Research Center, Animal Parasitic Diseases Laboratory, Beltsville, MD 20705-2350, USA.
United States Department of Agriculture, Agricultural Research Service, Beltsville Agricultural Research Center, Animal Parasitic Diseases Laboratory, Beltsville, MD 20705-2350, USA.
Res Vet Sci. 2020 Oct;132:292-307. doi: 10.1016/j.rvsc.2020.06.014. Epub 2020 Jun 26.
Toxoplasma gondii infections are common in humans and animals worldwide. Toxoplasmosis in goats continues to be of public health and economic concern. The present review summarizes worldwide information on the prevalence of clinical and subclinical infections, epidemiology, diagnosis, treatment, and genetic diversity of T. gondii in goats in the past decade. There is debate and uncertainty regarding excretion of T. gondii in milk and the ingestion of raw milk as sources of T. gondii infection for humans. Toxoplasmosis can cause abortion and deaths even in adult goats. PCR-RFLP typing of T. gondii DNA derived from viable T. gondii isolates has revealed genetic diversity in goats in North and South America. The significance of T. gondii isolates in domestic goats usually associated with wildlife in USA is discussed. This review will be of interest to biologists, parasitologists, veterinarians, and public health workers.
刚地弓形虫感染在全球范围内的人类和动物中很常见。山羊弓形虫病仍然是公共卫生和经济关注的问题。本综述总结了过去十年中全球有关山羊临床和亚临床感染的流行率、流行病学、诊断、治疗和弓形虫遗传多样性的信息。关于弓形虫在牛奶中的排泄以及人类摄入生奶作为弓形虫感染源的问题存在争议和不确定性。弓形虫病甚至可以导致成年山羊流产和死亡。从活的弓形虫分离物中提取的弓形虫 DNA 的 PCR-RFLP 分型显示了南北美洲山羊的遗传多样性。讨论了与美国野生动物有关的家养山羊中弓形虫分离物的意义。本综述将引起生物学家、寄生虫学家、兽医和公共卫生工作者的兴趣。
