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2型生物标志物对哮喘诊断有帮助吗？

Are type-2 biomarkers of any help in asthma diagnosis?

作者信息

Nekoee Haleh, Graulich Emmanuel, Schleich Florence, Guissard Françoise, Paulus Virginie, Henket Monique, Donneau Anne Françoise, Louis Renaud

机构信息

Dept of Public Health, CHU Liege and University of Liege, Liege, Belgium.

Dept of Pneumology, CHU Liege and University of Liege, Liege, Belgium.

出版信息

ERJ Open Res. 2020 Jul 20;6(2). doi: 10.1183/23120541.00169-2020. eCollection 2020 Apr.

DOI:10.1183/23120541.00169-2020
PMID:32714964
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7369447/
Abstract

https://bit.ly/3hYnnHu.

摘要

https://bit.ly/3hYnnHu. （此为网址，一般保留原文不翻译）

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本文引用的文献

1
Bronchodilation Test with Inhaled Salbutamol Versus Bronchial Methacholine Challenge to Make an Asthma Diagnosis: Do They Provide the Same Information?吸入沙丁胺醇支气管舒张试验与支气管激发试验在哮喘诊断中的应用：二者提供的信息相同吗？
J Allergy Clin Immunol Pract. 2020 Feb;8(2):618-625.e8. doi: 10.1016/j.jaip.2019.09.007. Epub 2019 Sep 18.
2
Priorities for future research into asthma diagnostic tools: A PAN-EU consensus exercise from the European asthma research innovation partnership (EARIP).未来哮喘诊断工具研究的重点：欧洲哮喘研究创新伙伴关系（EARIP）的泛欧共识实践。
Clin Exp Allergy. 2018 Feb;48(2):104-120. doi: 10.1111/cea.13080.
3
Effectiveness of inhaled corticosteroids in real life on clinical outcomes, sputum cells and systemic inflammation in asthmatics: a retrospective cohort study in a secondary care centre.吸入性糖皮质激素在实际临床中对哮喘患者临床结局、痰液细胞及全身炎症的有效性：一项二级医疗中心的回顾性队列研究
BMJ Open. 2017 Nov 28;7(11):e018186. doi: 10.1136/bmjopen-2017-018186.
4
Exacerbation risk and characterisation of the UK's asthma population from infants to old age.从婴儿到老年，英国哮喘人群的恶化风险及特征。
Thorax. 2018 Apr;73(4):313-320. doi: 10.1136/thoraxjnl-2017-210650. Epub 2017 Oct 26.
5
After asthma: redefining airways diseases.哮喘之后：重新定义气道疾病。
Lancet. 2018 Jan 27;391(10118):350-400. doi: 10.1016/S0140-6736(17)30879-6. Epub 2017 Sep 11.
6
Is it possible to claim or refute sputum eosinophils ≥ 3% in asthmatics with sufficient accuracy using biomarkers?是否有可能使用生物标志物以足够的准确性判定或否定哮喘患者痰液嗜酸性粒细胞≥3%？
Respir Res. 2017 Jul 3;18(1):133. doi: 10.1186/s12931-017-0615-9.
7
Reevaluation of Diagnosis in Adults With Physician-Diagnosed Asthma.成人医师诊断哮喘的再评估。
JAMA. 2017 Jan 17;317(3):269-279. doi: 10.1001/jama.2016.19627.
8
Accuracy of FENO for diagnosing asthma: a systematic review.呼出气一氧化氮检测诊断哮喘的准确性：系统评价。
Thorax. 2017 Feb;72(2):109-116. doi: 10.1136/thoraxjnl-2016-208704. Epub 2016 Jul 7.
9
Type 2 inflammation in asthma--present in most, absent in many.哮喘中的2型炎症——多数存在，许多不存在。
Nat Rev Immunol. 2015 Jan;15(1):57-65. doi: 10.1038/nri3786.
10
Biomarker-based asthma phenotypes of corticosteroid response.基于生物标志物的皮质类固醇反应性哮喘表型
J Allergy Clin Immunol. 2015 Apr;135(4):877-883.e1. doi: 10.1016/j.jaci.2014.10.026. Epub 2014 Dec 6.