Vermont Center on Behavior and Health, University of Vermont, United States of America; Department of Psychiatry, University of Vermont, United States of America.
Vermont Center on Behavior and Health, University of Vermont, United States of America.
Prev Med. 2020 Nov;140:106221. doi: 10.1016/j.ypmed.2020.106221. Epub 2020 Jul 24.
Accumulating evidence suggests that the hypothetical Cigarette Purchase Task (CPT), especially its demand Intensity index (i.e., estimated cigarettes participants would smoke if free), is associated with individual differences in smoking risk. Nevertheless, few studies have examined the extent to which hypothetical CPT demand Intensity may differ from consumption when participants are provided with free cigarettes. That topic is the overarching focus of the present study. Participants were 745 adult smokers with co-morbid psychiatric conditions or socioeconomic disadvantage. CPT was administered for usual-brand cigarettes prior to providing participants with seven days of their usual-brand cigarettes free of cost and consumption was recorded daily via an Interactive Voice Response (IVR) System. Demand Intensity was correlated with IVR smoking rate (rs 0.670-0.696, ps < 0.001) but estimates consistently exceeded IVR smoking rates by an average of 4.4 cigarettes per day (ps < 0.001). Importantly, both measures were comparably sensitive to discerning well-established differences in smoking risk, including greater cigarettes per day among men versus women (F(1,732) = 18.74, p < 0.001), those with versus without opioid-dependence (F(1,732) = 168.37, p < 0.001), younger versus older adults (F(2,730) = 32.93, p < 0.001), and those with lower versus greater educational attainment (F(1,732) = 38.26, p < 0.001). Overall, CPT demand Intensity appears to overestimate consumption rates relative to those observed when participants are provided with free cigarettes, but those deviations are systematic (i.e., consistent in magnitude and direction, Fs all <1.63; ps > 0.19 for all interactions with subgroups). This suggests that demand Intensity was sensitive to established group differences in smoking rate, supporting its utility as an important measure of addiction potential.
越来越多的证据表明,假设的香烟购买任务(CPT),特别是其需求强度指数(即如果免费,参与者将吸烟的估计香烟数量),与吸烟风险的个体差异有关。然而,很少有研究检验参与者获得免费香烟时,假设的 CPT 需求强度与消费之间的差异程度。这是本研究的主要关注点。参与者是 745 名患有共病精神疾病或社会经济劣势的成年吸烟者。在为参与者提供七天免费的惯用品牌香烟之前,对 CPT 进行了管理,并通过交互式语音应答(IVR)系统每天记录消费情况。需求强度与 IVR 吸烟率呈正相关(rs0.670-0.696,ps<0.001),但估计值始终平均超过 IVR 吸烟率 4.4 支/天(ps<0.001)。重要的是,这两个指标都能敏感地区分吸烟风险的显著差异,包括男性与女性之间每天吸烟量的差异(F(1,732)=18.74,p<0.001),有与没有阿片类药物依赖的人之间的差异(F(1,732)=168.37,p<0.001),年轻与老年成年人之间的差异(F(2,730)=32.93,p<0.001),以及教育程度较低与较高的人之间的差异(F(1,732)=38.26,p<0.001)。总体而言,CPT 需求强度似乎高于参与者获得免费香烟时观察到的消费率,但这些偏差是系统性的(即,大小和方向一致,Fs 均<1.63;所有与亚组的交互作用的 ps 值均>0.19)。这表明需求强度对吸烟率的既定群体差异敏感,支持其作为衡量成瘾潜力的重要指标的实用性。