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利奥波德·奥厄巴赫在血管系统领域的成就。

Leopold Auerbach's achievements in the field of vascular system.

机构信息

Specialist Medical Practice-Pathologist, Warsaw-Marymont, Bieniewicka 10, 01-632, Warsaw, Poland.

Department of Law of Public Finances, Faculty of Law, University of Bialystok, 15-213, Bialystok, Poland.

出版信息

Angiogenesis. 2020 Nov;23(4):577-579. doi: 10.1007/s10456-020-09739-5. Epub 2020 Jul 28.

Abstract

The scientific activity of Leopold Auerbach (1828-1897) was associated with Wrocław (Brelsau) medical school, which was renowned for brilliant descriptors of cardiovascular system, whose world-famous achievements became eponymous in history of medicine. Such terms as plexus myentericus Auerbach and Friedreich-Auerbach disease are still used worldwide. Little is known about the fact that the vascular system was at least as important in his scientific impact as neuromuscular field. Actually, one could realize that ganglion cells, which were previously discovered in cardiac location, were identified by Auerbach at interface between circular and longitudinal layer of intestinal tunica muscularis proporia. Consequently, Auerbach focused closely on vessels after examination of neural and muscular components of selected parts of gastrointestinal tract. Namely, he noticed that tightly grouped cells that formed vessels in the process of vasculogenesis and angiogenesis to constitute the lining of capillaries, possessed nuclei.

摘要

利奥波德·奥厄巴赫(Leopold Auerbach)(1828-1897)的科学活动与弗罗茨瓦夫(Brelsau)医学院有关,该医学院以心血管系统的杰出描述者而闻名,其举世闻名的成就成为医学史上的代名词。plexus myentericus Auerbach 和 Friedreich-Auerbach 病等术语至今仍在全球范围内使用。鲜为人知的是,血管系统在他的科学影响力中至少与神经肌肉领域同样重要。实际上,人们可以意识到,先前在心脏位置发现的神经节细胞是由奥厄巴赫在肠壁固有肌中环层和纵层交界处识别出来的。因此,奥厄巴赫在检查了胃肠道的选定部位的神经和肌肉成分后,密切关注血管。具体来说,他注意到在血管生成和血管生成过程中形成血管的紧密聚集的细胞构成了毛细血管的衬里,这些细胞具有细胞核。

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