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常规护理中妊娠生活方式干预后婴儿生命第一年的生长情况-来自集群随机 GeliS 试验的结果。

Infant growth during the first year of life following a pregnancy lifestyle intervention in routine care-Findings from the cluster-randomised GeliS trial.

机构信息

Else Kröner-Fresenius-Centre for Nutritional Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.

Competence Centre for Nutrition, Freising, Germany.

出版信息

Pediatr Obes. 2021 Feb;16(2):e12705. doi: 10.1111/ijpo.12705. Epub 2020 Jul 28.

DOI:10.1111/ijpo.12705
PMID:32725809
Abstract

BACKGROUND

Lifestyle interventions in pregnancy may influence postpartum development and obesity risk in offspring. The impact of lifestyle interventions as health system-based approaches is unclear.

OBJECTIVE

To evaluate the effect of an antenatal lifestyle intervention conducted as public health approach on infant development and feeding practices.

METHODS

We followed offspring born to women participating in the cluster-randomised GeliS trial who received usual care (CG) or repeated lifestyle counselling (IG). We collected data on offspring development and complementary feeding until the 12 month postpartum.

RESULTS

Of the 1998 mother-child pairs, 1783 completed the follow-up. Mean infant weight at 12 months was comparable between groups (IG: 9497.9 ± 1137.0 g; CG: 9433.4 ± 1055.2 g; P = .177). There was no significant evidence of differences in sex- and age-adjusted z-scores or in the odds of offspring being overweight. More infants in the IG received whole-grain products compared to the CG (95.6% vs. 90.8%; P = .003). Despite small differences in the timing of introducing solid foods, there were no further significant differences in the pattern of complementary feeding.

CONCLUSIONS

The antenatal lifestyle intervention embedded in routine care did not substantially influence infant anthropometrics and is thus unlikely to impact future development.

摘要

背景

孕期生活方式干预可能会影响后代产后的发育和肥胖风险。以健康系统为基础的生活方式干预的影响尚不清楚。

目的

评估作为公共卫生措施的产前生活方式干预对婴儿发育和喂养实践的影响。

方法

我们对参加了以群组为基础的 GeliS 试验的女性所生的后代进行了随访,这些女性接受了常规护理(CG)或重复的生活方式咨询(IG)。我们收集了婴儿发育和补充喂养的数据,直到产后 12 个月。

结果

在 1998 对母婴对中,有 1783 对完成了随访。12 个月时婴儿体重的平均值在两组之间无显著差异(IG:9497.9±1137.0 g;CG:9433.4±1055.2 g;P=.177)。在性别和年龄调整后的 z 评分或超重的后代的几率方面,没有明显的差异。与 CG 组相比,IG 组更多的婴儿接受了全麦产品(95.6%对 90.8%;P =.003)。尽管固体食物引入的时间略有差异,但在补充喂养的模式上没有进一步的显著差异。

结论

嵌入常规护理中的产前生活方式干预并没有显著影响婴儿的人体测量学指标,因此不太可能影响未来的发育。

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