Cho Haechan, Kang Jeehoon, Kim Hyo Soo, Park Kyung Woo
Department of Internal Medicine, Cardiovascular Center, Seoul National University Hospital, Seoul, Korea.
Korean Circ J. 2020 Aug;50(8):645-657. doi: 10.4070/kcj.2020.0098.
Oral antithrombotic therapy (antiplatelet therapy and anticoagulation therapy) is a key element of pharmacotherapy in patients with cardiovascular (CV) disease. Several reports of ethnic differences have suggested that there may be difference therapeutic requirements and response to therapy for antithrombotic therapy. In particular for East Asians, there seems to be a lower incidence of ischemic outcomes and a higher incidence of bleeding outcomes compared to Westerners. The purpose of this review is to describe the ethnicity-related differences in antithrombotic therapy for CV disease and to discuss the need to establish a more effective and targeted antithrombotic treatment strategy in East Asians.
口服抗栓治疗（抗血小板治疗和抗凝治疗）是心血管疾病患者药物治疗的关键要素。多项关于种族差异的报告表明，抗栓治疗的治疗需求和对治疗的反应可能存在差异。特别是对于东亚人，与西方人相比，缺血性结局的发生率似乎较低，而出血性结局的发生率较高。本综述的目的是描述心血管疾病抗栓治疗中与种族相关的差异，并讨论在东亚人中建立更有效、更具针对性的抗栓治疗策略的必要性。
