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佛罗里达袖状成形术在二叶式主动脉瓣与三叶式主动脉瓣患者中的疗效比较。

Outcomes of Florida Sleeve Procedure in Patients with Bicuspid Versus Tricuspid Aortic Valve.

机构信息

3463 Department of Medicine, University of Florida, Gainesville, FL, USA.

Division of Thoracic and Cardiovascular Surgery, Department of Surgery, University of Florida, Gainesville, FL, USA.

出版信息

Innovations (Phila). 2020 Jul/Aug;15(4):361-368. doi: 10.1177/1556984520938470. Epub 2020 Jul 30.

Abstract

OBJECTIVE

Outcomes of the Florida Sleeve (FS) procedure in patients with bicuspid aortic valve (BAV) have not been reported before. We compared outcomes of the FS procedure between patients with BAV and those with tricuspid aortic valve (TAV).

METHODS

From May 1, 2002 to January 1, 2016, 177 patients including 18 BAV and 159 TAV underwent the FS procedure. Baseline characteristics, perioperative outcomes, and echocardiographic measurements were compared between the 2 groups. Kaplan-Meier and life-table analyses were used to evaluate survival and freedom from reintervention rates.

RESULTS

Mean ± standard deviation age and aortic root diameter were comparable in BAV and TAV groups, 47.83 ± 11.19 versus 49.59 ± 15.79 years ( = 0.55) and 56.57 ± 6.18 versus 55.17 ± 8.84 mm ( = 0.46), respectively. The 30-day mortality and stroke rates were zero in the BAV group and 1.88% ( = 3) in the TAV group ( = 1.00). One patient (5.55%) in the BAV group and 8 (5.03%) patients in the TAV group needed permanent pacemaker implantation ( = 0.62). Freedom from reoperation was 93% in the BAV group and 99% in the TAV group at 8 years ( = 0.041). Patient survival rate was 100% in the BAV group and 91% in the TAV group at 8 years ( = 0.42). Freedom from aortic insufficiency greater than mild was 93% in the BAV group and 96.5% in the TAV group at 5 years ( = 0.61).

CONCLUSIONS

This is the first study reporting outcomes of the FS procedure in patients with BAV. This technique is feasible, and the results appear to be durable when compared to patients with TAV.

摘要

目的

在患有二叶式主动脉瓣(BAV)的患者中,佛罗里达袖套(FS)手术的结果尚未报道。我们比较了 BAV 患者和三叶式主动脉瓣(TAV)患者 FS 手术的结果。

方法

2002 年 5 月 1 日至 2016 年 1 月 1 日,177 例患者包括 18 例 BAV 和 159 例 TAV 接受 FS 手术。比较两组间的基线特征、围手术期结果和超声心动图测量值。Kaplan-Meier 和寿命表分析用于评估生存率和免于再次干预的比率。

结果

BAV 和 TAV 组的平均年龄和主动脉根部直径分别为 47.83±11.19 岁和 49.59±15.79 岁(=0.55)和 56.57±6.18 毫米和 55.17±8.84 毫米(=0.46)。BAV 组的 30 天死亡率和卒中率均为零,而 TAV 组为 1.88%(=3)(=1.00)。BAV 组 1 例(5.55%)患者和 TAV 组 8 例(5.03%)患者需要永久性起搏器植入(=0.62)。BAV 组 8 年免于再次手术的比例为 93%,TAV 组为 99%(=0.041)。BAV 组 8 年的患者生存率为 100%,TAV 组为 91%(=0.42)。BAV 组 5 年免于主动脉瓣关闭不全大于轻度的比例为 93%,TAV 组为 96.5%(=0.61)。

结论

这是首例报道 BAV 患者 FS 手术结果的研究。与 TAV 患者相比,该技术是可行的,结果似乎持久。

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