Department of Cardiac Surgery, Upper-Silesian Heart Center, Katowice, Poland.
Department of Cardiac Surgery, Medical University of Silesia, Faculty of Medical Sciences, Katowice, Poland.
Eur J Cardiothorac Surg. 2021 Jun 14;59(6):1183-1190. doi: 10.1093/ejcts/ezaa462.
The aim of this study was to compare the outcomes of tricuspid aortic valve (TAV) and bicuspid aortic valve (BAV) repair.
We assessed mortality, freedom from reoperation and the rate of aortic valve regurgitation recurrence. Mortality in both groups was compared with expected survival, and risk factors for reoperation were identified.
From January 2010 to April 2020, a total of 368 elective aortic valve repair procedures were performed, including 223 (60.6%) in patients with TAV. The perioperative mortality was 0.7% in the BAV group and 3.6% in the TAV group (P = 0.079). Estimated survival at 5 years in the BAV versus TAV group was 97 ± 3% vs 80 ± 6%, respectively (P < 0.001). Freedom from reoperation at 5 years in the TAV versus BAV group was 96 ± 3% vs 93 ± 4%, respectively (P = 0.28). Grade 2 or more aortic valve regurgitation was noted in 9.9% of BAV patients and 11% of TAV patients (P = 0.66). Reoperation was predicted by cusp perforation [hazard ratio 15.86 (4.44-56.61); P < 0.001], the use of pericardial patch [hazard ratio 8.58 (1.96-37.53); P = 0.004] and aortic valve annulus diameter >27.5 mm [hazard ratio 3.07 (0.99-9.58); P = 0.053].
BAV repair is as durable as TAV repair. BAV is not a predictor of a higher rate of reoperations. BAV repair yields survival comparable to expected. Cusp perforation, aortic valve annulus diameter >27.5 mm and the use of pericardial patch adversely impact long-term outcome of aortic valve repair.
本研究旨在比较三尖瓣主动脉瓣(TAV)和二叶式主动脉瓣(BAV)修复的结果。
我们评估了死亡率、免于再次手术的生存率和主动脉瓣反流复发率。比较两组患者的死亡率与预期生存率,并确定再次手术的危险因素。
2010 年 1 月至 2020 年 4 月,共进行了 368 例择期主动脉瓣修复手术,其中 TAV 患者 223 例(60.6%)。BAV 组围手术期死亡率为 0.7%,TAV 组为 3.6%(P=0.079)。BAV 组和 TAV 组的 5 年估计生存率分别为 97±3%和 80±6%(P<0.001)。TAV 组和 BAV 组的 5 年免于再次手术生存率分别为 96±3%和 93±4%(P=0.28)。BAV 患者中有 9.9%和 TAV 患者中有 11%出现 2 级或更高级别的主动脉瓣反流(P=0.66)。瓣叶穿孔(危险比 15.86[4.44-56.61];P<0.001)、使用心包补片(危险比 8.58[1.96-37.53];P=0.004)和主动脉瓣环直径>27.5 mm(危险比 3.07[0.99-9.58];P=0.053)是再次手术的预测因素。
BAV 修复与 TAV 修复一样持久。BAV 不是再次手术率较高的预测因素。BAV 修复的生存率与预期相符。瓣叶穿孔、主动脉瓣环直径>27.5 mm 和使用心包补片对主动脉瓣修复的长期结果产生不利影响。