Hu Yibo, Zeng Hongliang, Huang Jinhua, Jiang Ling, Chen Jing, Zeng Qinghai
Department of Dermatology, Third Xiangya Hospital, Central South University, Changsha, China.
Institute of Chinese Materia Medica, Hunan Academy of Chinese Medicine, Changsha, China.
Front Pharmacol. 2020 Jul 7;11:982. doi: 10.3389/fphar.2020.00982. eCollection 2020.
In Asia, the market for whitening cosmetics is expanding rapidly, more and more people prefer to use natural products. Driven by natural product demand and technical advances, herbal research is also developing fast. Lots of studies reported that Asian herbal reagents can reduce melanogenesis, these findings provide evidence for the whitening application of Asian herbs. However, the current development status and challenges of herbal research need attention too. By reviewing these studies, different problems in studying herbal formulas, extracts, and active ingredients were presented. One of the most influential troubles is that the components of herbs are too complex to obtain reliable results. Thus, an understanding of the overall quality of herbal research is necessary. Further, 90 most cited Asian herbal studies on whitening were collected, which were conducted between 2017 and 2020, then statistical analysis was carried out. This work provided a comprehensive understanding of Asian herbal research in skin whitening, including the overall status and quality, as well as the focuses and limitations of these studies. By proactively confronting and analyzing these issues, it is suggested that the focus of herbal medicine research needs to shift from quantity to quality, and the new stage of development should emphasize transformation from research findings to whitening products.
在亚洲,美白化妆品市场正在迅速扩张,越来越多的人更喜欢使用天然产品。在天然产品需求和技术进步的推动下,草药研究也在快速发展。许多研究报告称,亚洲草药试剂可以减少黑色素生成,这些发现为亚洲草药在美白方面的应用提供了证据。然而,草药研究的当前发展状况和挑战也需要关注。通过回顾这些研究,呈现了在研究草药配方、提取物和活性成分时存在的不同问题。最具影响力的问题之一是草药成分过于复杂,难以获得可靠的结果。因此,有必要了解草药研究的整体质量。此外,收集了2017年至2020年间发表的90篇被引用次数最多的关于亚洲草药美白的研究,然后进行了统计分析。这项工作提供了对亚洲草药在皮肤美白研究方面的全面理解,包括总体状况和质量,以及这些研究的重点和局限性。通过积极面对和分析这些问题,建议草药医学研究的重点需要从数量转向质量,新的发展阶段应强调从研究成果向美白产品的转化。