Kim Su-Yeon, Kang Seok-Seong
Department of Food Science and Biotechnology, College of Life Science and Biotechnology, Dongguk University-Seoul, Goyang 10326, Korea.
Food Sci Anim Resour. 2020 Jul;40(4):668-674. doi: 10.5851/kosfa.2020.e42. Epub 2020 Jul 1.
Manuka honey (MH) has been shown anti-bacterial activity against several pathogenic bacteria. However, the inhibitory effect of MH on biofilm formation by O157:H7 has not yet been examined. In this study, MH significantly reduced O157:H7 biofilm. Moreover, pre- and post-treatment with MH also significantly reduced O157:H7 biofilm. Cellular metabolic activities exhibited that the viability of O157:H7 biofilm cells was reduced in the presence of MH. Further, colony forming unit of MH-treated O157:H7 biofilm was significantly reduced by over 70%. Collectively, this study suggests the potential of anti-biofilm properties of MH which could be applied to control O157:H7.
麦卢卡蜂蜜（MH）已显示出对多种病原菌的抗菌活性。然而，MH对O157:H7生物膜形成的抑制作用尚未得到研究。在本研究中，MH显著减少了O157:H7生物膜。此外，用MH进行预处理和后处理也显著减少了O157:H7生物膜。细胞代谢活性表明，在MH存在的情况下，O157:H7生物膜细胞的活力降低。此外，经MH处理的O157:H7生物膜的菌落形成单位显著减少了70%以上。总体而言，本研究表明MH具有抗生物膜特性的潜力，可用于控制O157:H7。
