Department of Allergy and Immunology, Veterans Affairs Caribbean Healthcare System, San Juan, Puerto Rico.
Department of Allergy and Immunology, COSSMA, Las Piedras, Puerto Rico.
Pediatr Rev. 2020 Aug;41(8):403-415. doi: 10.1542/pir.2019-0037.
Food allergy is 1 of the 4 manifestations of the "atopic march," along with eczema, allergic rhinitis, and asthma. Depending on the pathophysiologic immune mechanisms behind a food allergy, it can be classified as immunoglobulin E-mediated, non-immunoglobulin E-mediated, or mixed. The prevalence of food allergies has risen worldwide during the past few decades, becoming a significant global health concern. Patients experiencing food allergies and their caregivers are heavily burdened personally, socially, emotionally, and financially. The health-care system is also considerably affected. Pediatricians, as primary health-care providers, are often challenged with these patients, becoming the first-line for the recognition and management of food allergies. The purpose of this review is to provide a comprehensive summary of food allergies, including the most up-to-date information, recent guidelines, and recommendations.
食物过敏是“特应性进程”的 4 种表现之一,其余 3 种为湿疹、过敏性鼻炎和哮喘。根据食物过敏背后的病理生理免疫机制,它可以分为免疫球蛋白 E 介导、非免疫球蛋白 E 介导或混合介导。在过去几十年中,食物过敏的患病率在全球范围内有所上升,成为一个重大的全球健康问题。患有食物过敏的患者及其护理人员在个人、社会、情感和经济方面都承受着沉重的负担。医疗保健系统也受到了很大的影响。儿科医生作为初级保健提供者,经常面临这些患者,成为识别和管理食物过敏的第一线。本综述的目的是提供食物过敏的全面概述,包括最新信息、最新指南和建议。