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Low-dose lithium against dementia.

作者信息

Baethge Christopher

机构信息

Department of Psychiatry and Psychotherapy, Faculty of Medicine, University of Cologne Medical School, Kerpener Str. 62, 50931, Cologne, Germany.

出版信息

Int J Bipolar Disord. 2020 Aug 3;8(1):25. doi: 10.1186/s40345-020-00188-z.

DOI:10.1186/s40345-020-00188-z
PMID:32743689
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7396410/
Abstract
摘要

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Low-dose lithium against dementia.低剂量锂盐预防痴呆症。
Int J Bipolar Disord. 2020 Aug 3;8(1):25. doi: 10.1186/s40345-020-00188-z.
2
Does lithium therapy protect against the onset of dementia?锂疗法能预防痴呆症的发作吗？
Alzheimer Dis Assoc Disord. 2005 Jan-Mar;19(1):20-2. doi: 10.1097/01.wad.0000155068.23937.9b.
3
Does lithium protect against dementia?锂对预防痴呆症有作用吗？
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4
Lithium treatment and risk of dementia.锂治疗与痴呆风险
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Population Studies of Association Between Lithium and Risk of Neurodegenerative Disorders.锂与神经退行性疾病风险之间关联的人群研究
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[Dementia and bipolar disorder on the borderline of old age].[老年边缘的痴呆症和双相情感障碍]
Psychiatriki. 2013 Apr-Jun;24(2):132-44.
7
Does long-term medication with lithium, clozapine or antidepressants prevent or attenuate dementia in bipolar and depressed patients?锂、氯氮平或抗抑郁药的长期用药是否能预防或减轻双相和抑郁患者的痴呆？
Int J Psychiatry Clin Pract. 2007;11(1):2-8. doi: 10.1080/13651500600810133.
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Association of Lithium in Drinking Water With the Incidence of Dementia.饮用水中锂与痴呆症发病率的关联
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A case with reversible neurotoxicity after 2 years of dementia secondary to maintenance lithium treatment.一例因长期锂盐治疗导致痴呆两年后出现可逆性神经毒性的病例。
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引用本文的文献

1
Microdose lithium improves behavioral deficits and modulates molecular mechanisms of memory formation in female SAMP-8, a mouse model of accelerated aging.微量锂改善雌性 SAMP-8（加速衰老小鼠模型）的行为缺陷，并调节记忆形成的分子机制。
PLoS One. 2024 Apr 4;19(4):e0299534. doi: 10.1371/journal.pone.0299534. eCollection 2024.
2
Lithium produces bi-directionally regulation of mood disturbance, acts synergistically with anti-depressive/-manic agents, and did not deteriorate the cognitive impairment in murine model of bipolar disorder.锂对心境障碍具有双向调节作用，与抗抑郁/抗躁狂药物具有协同作用，并且不会恶化双相情感障碍小鼠模型的认知障碍。
Transl Psychiatry. 2022 Sep 2;12(1):359. doi: 10.1038/s41398-022-02087-6.

本文引用的文献

1
Clinical use of lithium salts: guide for users and prescribers.锂盐的临床应用：使用者及开处方者指南。
Int J Bipolar Disord. 2019 Jul 22;7(1):16. doi: 10.1186/s40345-019-0151-2.
2
Clinical and biological effects of long-term lithium treatment in older adults with amnestic mild cognitive impairment: randomised clinical trial.长期锂治疗对遗忘型轻度认知障碍老年患者的临床和生物学影响：随机临床试验。
Br J Psychiatry. 2019 Nov;215(5):668-674. doi: 10.1192/bjp.2019.76.
3
Association of Lithium in Drinking Water With the Incidence of Dementia.饮用水中锂与痴呆症发病率的关联
JAMA Psychiatry. 2017 Oct 1;74(10):1005-1010. doi: 10.1001/jamapsychiatry.2017.2362.
4
Long-Term Acute-Phase Treatment With Antidepressants, 8 Weeks and Beyond: A Systematic Review and Meta-Analysis of Randomized, Placebo-Controlled Trials.抗抑郁药的长期急性期治疗：8 周及以上的随机、安慰剂对照试验的系统评价和荟萃分析。
J Clin Psychiatry. 2018 Jan/Feb;79(1). doi: 10.4088/JCP.15r10545.
5
Computerized Cognitive Training in Older Adults With Mild Cognitive Impairment or Dementia: A Systematic Review and Meta-Analysis.计算机化认知训练对轻中度认知障碍或痴呆老年人的影响：系统评价和荟萃分析。
Am J Psychiatry. 2017 Apr 1;174(4):329-340. doi: 10.1176/appi.ajp.2016.16030360. Epub 2016 Nov 14.
6
Lithium treatment and risk for dementia in adults with bipolar disorder: population-based cohort study.锂治疗与双相情感障碍成人痴呆风险：基于人群的队列研究。
Br J Psychiatry. 2015 Jul;207(1):46-51. doi: 10.1192/bjp.bp.114.154047. Epub 2015 Jan 22.
7
Prophylactic lithium treatment and cognitive performance in patients with a long history of bipolar illness: no simple answers in complex disease-treatment interplay.锂预防治疗与长期双相情感障碍患者的认知表现：复杂疾病-治疗相互作用中没有简单的答案。
Int J Bipolar Disord. 2014 Dec 24;2:1. doi: 10.1186/s40345-014-0016-7. eCollection 2014.
8
Disease-modifying properties of long-term lithium treatment for amnestic mild cognitive impairment: randomised controlled trial.长期锂治疗对遗忘型轻度认知障碍的疾病修饰作用：随机对照试验。
Br J Psychiatry. 2011 May;198(5):351-6. doi: 10.1192/bjp.bp.110.080044.