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当前金微纳米粒子在生物医学和诊断中的应用。

Current Biomedical and Diagnostic Applications of Gold Micro and Nanoparticles.

机构信息

Faculty of Military Health Sciences, University of Defense, Trebesska 1575, Hradec Kralove CZ-50001, Czech Republic.

出版信息

Mini Rev Med Chem. 2021;21(9):1085-1095. doi: 10.2174/1389557520666200730155616.

Abstract

Production of particles and their adaptation in the pharmacology became an object of interest, and they are the currently introduced therapies based on the use of micro and nanoparticles. The use of gold particles is not an exception. This review has focused on the application of gold micro and nanoparticles in pharmacology and biomedicine. The particles can be used for diagnosis respective theranostic of cancer, rheumatoid arthritis and as antimicrobial means. Besides these applications, specifications of gold, gold particles, and colloidal gold manufacturing and their comparison with the solid gold, are described as well. This review is based on a survey of actual scientific literature.

摘要

金纳米粒子的生产及其在药理学中的应用已成为研究热点,目前基于微纳米粒子的治疗方法也相继问世。金纳米粒子的应用也不例外。本文综述了金微纳米粒子在药理学和生物医学中的应用。这些粒子可用于癌症、类风湿关节炎的诊断和治疗,也可用作抗菌手段。此外,本文还描述了金、金纳米粒子和胶体金的制造规格,并与实体金进行了比较。本文综述基于对现有科学文献的调查。

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