口腔微生物群在口腔内口臭中的作用。
The Role of Oral Microbiota in Intra-Oral Halitosis.
作者信息
Hampelska Katarzyna, Jaworska Marcelina Maria, Babalska Zuzanna Łucja, Karpiński Tomasz M
机构信息
Department of Genetics and Pharmaceutical Microbiology, Poznań University of Medical Sciences, Święcickiego 4, 60-781 Poznań, Poland.
Central Microbiology Laboratory, H. Święcicki Clinical Hospital, Poznań University of Medical Sciences, Przybyszewskiego 49, 60-355 Poznań, Poland.
出版信息
J Clin Med. 2020 Aug 2;9(8):2484. doi: 10.3390/jcm9082484.
Halitosis is a common ailment concerning 15% to 60% of the human population. Halitosis can be divided into extra-oral halitosis (EOH) and intra-oral halitosis (IOH). The IOH is formed by volatile compounds, which are produced mainly by anaerobic bacteria. To these odorous substances belong volatile sulfur compounds (VSCs), aromatic compounds, amines, short-chain fatty or organic acids, alcohols, aliphatic compounds, aldehydes, and ketones. The most important VSCs are hydrogen sulfide, dimethyl sulfide, dimethyl disulfide, and methyl mercaptan. VSCs can be toxic for human cells even at low concentrations. The oral bacteria most related to halitosis are spp., spp., spp., spp., spp., spp., spp., spp., spp., spp., spp., , and spp. Most bacteria that cause halitosis are responsible for periodontitis, but they can also affect the development of oral and digestive tract cancers. Malodorous agents responsible for carcinogenesis are hydrogen sulfide and acetaldehyde.
口臭是一种常见疾病，影响着15%至60%的人群。口臭可分为口外口臭（EOH）和口内口臭（IOH）。口内口臭由挥发性化合物形成，这些化合物主要由厌氧菌产生。这些有气味的物质包括挥发性硫化合物（VSCs）、芳香化合物、胺类、短链脂肪酸或有机酸、醇类、脂肪族化合物、醛类和酮类。最重要的VSCs是硫化氢、二甲基硫醚、二甲基二硫醚和甲硫醇。即使在低浓度下，VSCs对人体细胞也可能有毒。与口臭最相关的口腔细菌有……菌属、……菌属、……菌属、……菌属、……菌属、……菌属、……菌属、……菌属、……菌属、……菌属、……菌属、……菌属、……菌属和……菌属。大多数导致口臭的细菌也是牙周炎的病因，但它们也会影响口腔和消化道癌症的发展。导致致癌的恶臭物质是硫化氢和乙醛。
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