Department of Medical Examination, Uji-Tokushukai Medical Center, Japan.
Department of Emergency and General Medicine, Uji-Tokushukai Medical Center, Japan.
Intern Med. 2020 Dec 1;59(23):2995-3000. doi: 10.2169/internalmedicine.4637-20. Epub 2020 Aug 4.
We herein report two cases of autoimmune gastritis without complete atrophy of the corpus. Both were positive for anti-parietal cell antibodies. Endoscopic examinations indicated that atrophic changes were predominant in the lesser curvature of the corpus in both cases. In one, the greater curvature was covered with pseudopolyp-like nodules, whereas the greater curvature of the other showed multiple similar nodules and mildly atrophic mucosa. Histopathological examinations of these nodules showed focal and patchy atrophy and preserved fundic glands with parietal cell pseudohypertrophy. Follow-up endoscopy and a repeated biopsy demonstrated the development of gastric atrophy on the greater curvature in both cases.
我们在此报告两例无胃体完全萎缩的自身免疫性胃炎。两例均为壁细胞抗体阳性。内镜检查提示两例均以胃体小弯为主的萎缩性改变。其中一例大弯覆盖假息肉样结节,另一例大弯见多个类似的结节和轻度萎缩的黏膜。这些结节的组织病理学检查显示局灶性和斑片状萎缩,胃底腺保留,壁细胞假性肥大。随访内镜和重复活检显示两例大弯均出现胃萎缩。