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番茄红素作为一种天然抗氧化剂用于预防人类健康紊乱。

Lycopene as a Natural Antioxidant Used to Prevent Human Health Disorders.

作者信息

Imran Muhammad, Ghorat Fereshteh, Ul-Haq Iahtisham, Ur-Rehman Habib, Aslam Farhan, Heydari Mojtaba, Shariati Mohammad Ali, Okuskhanova Eleonora, Yessimbekov Zhanibek, Thiruvengadam Muthu, Hashempur Mohammad Hashem, Rebezov Maksim

机构信息

University Institute of Diet and Nutritional Sciences, Faculty of Allied Health Sciences, The University of Lahore, Lahore 54000, Pakistan.

Non-Communicable Diseases Research Center, Sabzevar University of Medical Sciences, Sabzevar 9617913112, Iran.

出版信息

Antioxidants (Basel). 2020 Aug 4;9(8):706. doi: 10.3390/antiox9080706.

Abstract

Lycopene, belonging to the carotenoids, is a tetraterpene compound abundantly found in tomato and tomato-based products. It is fundamentally recognized as a potent antioxidant and a non-pro-vitamin A carotenoid. Lycopene has been found to be efficient in ameliorating cancer insurgences, diabetes mellitus, cardiac complications, oxidative stress-mediated malfunctions, inflammatory events, skin and bone diseases, hepatic, neural and reproductive disorders. This review summarizes information regarding its sources and uses amongst different societies, its biochemistry aspects, and the potential utilization of lycopene and possible mechanisms involved in alleviating the abovementioned disorders. Furthermore, future directions with the possible use of this nutraceutical against lifestyle-related disorders are emphasized. Its protective effects against recommended doses of toxic agents and toxicity and safety are also discussed.

摘要

番茄红素属于类胡萝卜素,是一种四萜化合物,大量存在于番茄及番茄制品中。它被公认为是一种强效抗氧化剂和非维生素A类胡萝卜素。研究发现,番茄红素在改善癌症发生、糖尿病、心脏并发症、氧化应激介导的功能障碍、炎症反应、皮肤和骨骼疾病、肝脏、神经和生殖系统紊乱等方面具有显著效果。本文综述了番茄红素在不同社会中的来源和用途、其生物化学特性,以及番茄红素的潜在应用和缓解上述疾病的可能机制。此外,还强调了这种营养保健品在预防与生活方式相关疾病方面的未来发展方向。同时,也讨论了其对推荐剂量有毒物质的保护作用以及毒性和安全性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/913d/7464847/21da37d91931/antioxidants-09-00706-g001.jpg

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