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都灵历史解剖报告所述的西班牙流感。

Spanish flu in Turin as told by historical autopsy reports.

机构信息

SC Anatomia Patologica Ospedale Cardinal Massaja, Asti, Italy.

出版信息

Pathologica. 2020 Jun;112(2):110-114. doi: 10.32074/1591-951X-2-20.

DOI:10.32074/1591-951X-2-20
PMID:32760055
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7931561/
Abstract

Spanish flu spread worldwide between 1918 and 1920 causing over 20 million deaths, exceeding even the number of deaths registered during the First World War (WWI). The main symptom of the disease was hemorrhagic tracheobronchitis, the onset of which was typically sudden and fatal. Young, healthy people died quickly. Despite the tragic impact of the disease on populations, already exhausted by the First World War, there is very little documentation. This was likely due to the severe censorship of the time. For this reason, autopsy reports can be a relevant source of information on the disease. Historical catalogues kept in Turin, where all autopsies were detailed, can be consulted. According to the "Regolamento di Polizia Mortuaria" dating back to 1892, autopsies were to be performed on all patients that died at home or in hospital. Therefore, autopsy reports showing the spread of diseases among the population can also help us obtain information about the spread of Spanish flu in Turin. While not documented, almost certainly the "Regolamento" was improperly implemented since just 45 cases of Spanish flu were reported, while deaths were most certainly daily and in their hundreds. According to autopsy reports, the first case occurred on 8th October 1918, although, the first official diagnosis is dated as being 24th November 1918. The records show that 18 people died during the first Italian pandemic wave. The second Italian pandemic wave seems to have been even more aggressive in Turin with 27 people having died between 8th January 1920 and 7th February 1920.

摘要

西班牙流感于 1918 年至 1920 年间在全球范围内传播,导致超过 2000 万人死亡,甚至超过了第一次世界大战(一战)期间的死亡人数。该病的主要症状是出血性气管支气管炎,其发病通常突然且致命。年轻、健康的人很快就死亡了。尽管这种疾病对已经因一战而疲惫不堪的人群造成了悲惨的影响,但几乎没有记录。这可能是由于当时的严格审查。因此,尸检报告可能是了解该疾病的相关信息来源。可以查阅都灵保存的历史目录,那里详细记录了所有的尸检。根据可追溯到 1892 年的《殡葬警察条例》,所有在家中或医院死亡的患者都应进行尸检。因此,显示疾病在人群中传播的尸检报告也可以帮助我们获取有关西班牙流感在都灵传播的信息。虽然没有记录,但几乎可以肯定《条例》没有得到正确执行,因为仅报告了 45 例西班牙流感病例,而死亡人数肯定是每天数百人。根据尸检报告,第一例病例发生在 1918 年 10 月 8 日,尽管第一例官方诊断日期为 1918 年 11 月 24 日。记录显示,有 18 人在意大利第一波大流行中死亡。在都灵,第二波意大利大流行似乎更为凶猛,有 27 人在 1920 年 1 月 8 日至 2 月 7 日期间死亡。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2344/7931561/0e32890aaa60/pathol-2020-02-110-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2344/7931561/0e32890aaa60/pathol-2020-02-110-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2344/7931561/0e32890aaa60/pathol-2020-02-110-g001.jpg

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本文引用的文献

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2
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3
A year of terror and a century of reflection: perspectives on the great influenza pandemic of 1918-1919.一年的恐惧和一个世纪的反思:对 1918-1919 年大流感的透视。
BMC Infect Dis. 2019 Feb 6;19(1):117. doi: 10.1186/s12879-019-3750-8.
4
"Spanish flu, or whatever it is...": The paradox of public health in a time of crisis.“西班牙流感,或者不管它叫什么……”:危机时期公共卫生的悖论。
Public Health Rep. 2010 Apr;125 Suppl 3(Suppl 3):38-47.
5
The Spanish influenza pandemic in occidental Europe (1918-1920) and victim age.西班牙流感大流行在西欧(1918-1920 年)和受害者年龄。
Influenza Other Respir Viruses. 2010 Mar;4(2):81-9. doi: 10.1111/j.1750-2659.2009.00125.x.
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The 1918 "Spanish flu" in Spain.1918年西班牙的“西班牙流感”。
Clin Infect Dis. 2008 Sep 1;47(5):668-73. doi: 10.1086/590567.
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Integrating historical, clinical and molecular genetic data in order to explain the origin and virulence of the 1918 Spanish influenza virus.整合历史、临床和分子遗传学数据,以解释1918年西班牙流感病毒的起源和毒力。
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