Collins S M
Intestinal Diseases Research Unit, McMaster University, Hamilton, Ont.
CMAJ. 1988 Feb 15;138(4):309-16.
The irritable bowel syndrome (IBS) is an extremely common disorder. It is believed to occur usually after emotional stress and perhaps because of behavioural and dietary factors. There is definite evidence of disturbed gastrointestinal function associated with IBS; however, a diagnostic marker remains elusive. The current trend is to diagnose IBS on the basis of the patient's history and the findings at physical examination and after minimal investigation. The physician-patient relationship remains the most important factor in the management of IBS. Long-term benefit may be achieved with the use of dietary fibre supplements or stool-bulking agents. The evaluation of currently available drugs is difficult because of the placebo effect. Drug therapy should be aimed at specific symptoms and used mainly during the initial phase of treatment.
肠易激综合征（IBS）是一种极为常见的疾病。人们认为它通常在情绪应激后发生，可能还与行为和饮食因素有关。有明确证据表明肠易激综合征与胃肠功能紊乱有关；然而，诊断标志物仍然难以捉摸。目前的趋势是根据患者的病史、体格检查结果以及经过最少的检查后诊断肠易激综合征。医患关系仍然是肠易激综合征管理中最重要的因素。使用膳食纤维补充剂或大便膨胀剂可能会获得长期益处。由于安慰剂效应，评估目前可用的药物很困难。药物治疗应针对特定症状，主要在治疗的初始阶段使用。
