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Relationship between rheumatoid arthritis and periodontal disease in Korean adults: Data from the Sixth Korea National Health and Nutrition Examination Survey, 2013 to 2015.韩国成年人类风湿关节炎与牙周病的关系:来自 2013 至 2015 年第六次韩国国家健康与营养调查的数据。
J Periodontol. 2019 Apr;90(4):350-357. doi: 10.1002/JPER.18-0290. Epub 2018 Nov 26.
2
Increased interleukin 1α and interleukin 1β expression is involved in the progression of periapical lesions in primary teeth.白细胞介素1α和白细胞介素1β表达增加参与乳牙根尖周病变的进展。
BMC Oral Health. 2018 Jul 16;18(1):124. doi: 10.1186/s12903-018-0586-3.
3
Development of Periapical Lesions in Endodontically Treated Teeth with and without Periodontal Involvement: A Retrospective Cohort Study.根管治疗后伴或不伴牙周炎的根尖病变的发展:一项回顾性队列研究。
J Endod. 2017 Aug;43(8):1246-1249. doi: 10.1016/j.joen.2017.03.037. Epub 2017 Jun 9.
4
Prevalence of Periapical Rarefying Osteitis in Patients with Rheumatoid Arthritis.类风湿关节炎患者根尖周稀疏性骨炎的患病率。
J Endod. 2017 Jul;43(7):1093-1096. doi: 10.1016/j.joen.2017.02.015. Epub 2017 May 2.
5
Association between apical periodontitis lesions and plasmatic levels of C-reactive protein, interleukin 6 and fibrinogen in hypertensive patients.高血压患者根尖周炎病变与血浆C反应蛋白、白细胞介素6和纤维蛋白原水平之间的关联
Int Endod J. 2016 Dec;49(12):1107-1115. doi: 10.1111/iej.12567. Epub 2015 Nov 20.
6
An overview on biologic medications and their possible role in apical periodontitis.生物药物概述及其在根尖周炎中的可能作用。
J Endod. 2014 Dec;40(12):1902-11. doi: 10.1016/j.joen.2014.08.013. Epub 2014 Oct 7.
7
Overlapping protective and destructive regulatory pathways in apical periodontitis.根尖周炎中重叠的保护性和破坏性调节途径。
J Endod. 2014 Feb;40(2):155-63. doi: 10.1016/j.joen.2013.10.036. Epub 2013 Dec 15.
8
The role of IL-6 on apical periodontitis: a systematic review.IL-6 在根尖周炎中的作用:一项系统评价。
Int Endod J. 2014 Jul;47(7):615-21. doi: 10.1111/iej.12196. Epub 2013 Nov 14.
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Can apical periodontitis modify systemic levels of inflammatory markers? A systematic review and meta-analysis.根尖周炎会改变全身炎症标志物水平吗?一项系统评价与荟萃分析。
J Endod. 2013 Oct;39(10):1205-17. doi: 10.1016/j.joen.2013.06.014. Epub 2013 Aug 16.
10
Association between chronic periodontitis and rheumatoid arthritis: a hospital-based case-control study.慢性牙周炎与类风湿关节炎的相关性:一项基于医院的病例对照研究。
Rheumatol Int. 2013 Jan;33(1):103-9. doi: 10.1007/s00296-011-2284-1. Epub 2012 Jan 7.

类风湿关节炎与根尖周炎的相关性:一项横断面研究。

Association between Rheumatoid Arthritis and Apical Periodontitis: A Cross-sectional Study.

机构信息

Department of Endodontics, Faculty of Dentistry, Atatürk University, Erzurum, Turkey.

Department of Physical Medicine and Rehabilitation, Medical Faculty of Atatürk University Erzurum, Turkey.

出版信息

Eur Endod J. 2020 Jul 22;5(2):155-158. doi: 10.14744/eej.2019.52824. eCollection 2020.

DOI:10.14744/eej.2019.52824
PMID:32766528
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7398985/
Abstract

OBJECTIVE

The present cross-sectional study aimed to investigate possible association between Rheumatoid Arthritis (RA) and Apical Periodontitis (AP).

METHODS

In table one it is mentioned 48 patients diagnosed with RA were included in the experimental group. Another 48 healthy age- and gender-matched participants who reported no history of any systemic disease were selected to form the control group. All the patients were examined radiographically and clinically to diagnose the presence of AP. The following data was recorded for all patients; the number of teeth present, the number of teeth with AP, the number of patients with AP, the number of patients with root canal treated teeth (RCT) and the number of patients with RCT+AP. The chi-square test and logistic regression analysis were used to determine the possible association between RA and AP.

RESULTS

A total of 1026 teeth were examined in the RA group and 45 of them was diagnosed as AP. In the control group, 1025 teeth were examined and 21 teeth were diagnosed as AP. It was found that the prevalence of teeth with AP (4.3%) was significantly higher in the RA group than the control (2%) (odds ratio [OR]=2.193, P=0.003). Logistic regression analysis showed that RA is significantly associated with AP.

CONCLUSION

It can be concluded that patients with RA can be more prone to develop AP.

摘要

目的

本横断面研究旨在探讨类风湿关节炎(RA)与根尖周炎(AP)之间可能存在的关联。

方法

在表 1 中提到,纳入了 48 例确诊为 RA 的患者作为实验组。另外选择了 48 名年龄和性别匹配、无任何系统性疾病史的健康参与者作为对照组。所有患者均进行影像学和临床检查以诊断 AP 的存在。记录所有患者的数据如下:存在的牙齿数、患有 AP 的牙齿数、患有 AP 的患者数、接受根管治疗的牙齿数(RCT)和接受 RCT+AP 的患者数。采用卡方检验和 logistic 回归分析来确定 RA 和 AP 之间可能存在的关联。

结果

在 RA 组共检查了 1026 颗牙齿,其中 45 颗被诊断为 AP。在对照组中,共检查了 1025 颗牙齿,其中 21 颗被诊断为 AP。结果发现,RA 组患有 AP 的牙齿比例(4.3%)明显高于对照组(2%)(比值比[OR]=2.193,P=0.003)。logistic 回归分析表明,RA 与 AP 显著相关。

结论

可以得出结论,RA 患者更容易发生 AP。