State Key Laboratory of Heavy Oil Processing, College of Chemical Engineering, China University of Petroleum, Qingdao, Shandong, 266580, China.
College of Environment and Resources, Xiangtan University, Xiangtan, Hunan Province, 411105, China.
Chem Rec. 2020 Nov;20(11):1236-1256. doi: 10.1002/tcr.202000055. Epub 2020 Aug 7.
With increasing interest in developing biodegradable polymers to replace fossil-based products globally, lactic acid (LA) has been paid extensive attention due to the high environment-compatibility of its downstream products. The mainstream efforts have been put in developing energy-efficient conversion technologies through biological and chemical routes to synthesize LA. However, to our best knowledge, there is a lack of sufficient attention in developing effective separation technologies with high atom economics for purifying LA and derivatives. In this review, the most recent advances in purifying LA using precipitation, reactive extraction, emulsion liquid membrane, reactive distillation, molecular distillation, and membrane techniques will be discussed critically with respect to the fundamentals, flow scheme, energy efficiency, and equipment. The outcome of this article is to offer insights into implementing more atomic and energy-efficient technologies for upgrading LA.
随着人们对开发可生物降解聚合物以替代全球基于化石的产品的兴趣日益浓厚，由于其下游产品具有很高的环境相容性，乳酸（LA）受到了广泛关注。主流的努力是通过生物和化学途径开发节能转化技术来合成 LA。然而，据我们所知，在开发具有高原子经济性的有效分离技术以纯化 LA 和衍生物方面，还没有得到足够的重视。在这篇综述中，将批判性地讨论使用沉淀、反应萃取、乳状液膜、反应蒸馏、分子蒸馏和膜技术纯化 LA 的最新进展，涉及基础、流程方案、能效和设备。本文的目的是为实施更原子经济性和更节能的技术来升级 LA 提供思路。
