使用光学相干断层扫描血管造影术测量视网膜静脉阻塞患者黄斑无血管区的可靠性
Reliability of foveal avascular zone measurements in eyes with retinal vein occlusion using optical coherence tomography angiography.
作者信息
de Oliveira Bruno Mauricio Rodrigues, Nakayama Luis Filipe, de Godoy Bruno Rebello, de Azevedo Alexandre Gomes Bortoloti, Hirai Flavio Eduardo, Mitne Somaia
机构信息
Retina and Vitreous Sector, Department of Ophthalmology, Universidade Federal de São Paulo - Escola Paulista de Medicina, Rua Botucatu, 821, Vila Clementino, São Paulo, SP 04023-062 Brazil.
出版信息
Int J Retina Vitreous. 2020 Aug 3;6:35. doi: 10.1186/s40942-020-00237-w. eCollection 2020.
BACKGROUND
To evaluate the reliability of foveal avascular zone (FAZ) area measurements using optical coherence tomography angiography (OCTA) in eyes with retinal vein occlusion (RVO).
METHODS
Twenty-five OCTA exams of patients with RVO were evaluated retrospectively. Three examiners performed manual measurements of the FAZ, and interrater and intrarater reliability were obtained.
RESULTS
The intraclass correlation coefficient (ICC) for interrater reliability for individual measurements was 0.62 (moderate) with a 95% confidence interval (CI) of 0.40 to 0.79 (p < 0.001). The ICC (95% CI) for intrarater reliability was 0.92 (0.82 to 0.96) for rater A, 0.96 (0.91 to 0.98) for B, and 0.88 (0.76 to 0.94) for C (p < 0.001). In all subanalyses including presence of edema and type of occlusion, interrater reliability was poor/moderate, and intrarater reliability was good/excellent.
CONCLUSION
The FAZ varies significantly among eyes with RVO, so measurements obtained using OCTA should be analyzed with caution due to the moderate level of reliability among different examiners.
背景
评估光学相干断层扫描血管造影（OCTA）测量视网膜静脉阻塞（RVO）患者黄斑无血管区（FAZ）面积的可靠性。
方法
回顾性评估25例RVO患者的OCTA检查。三名检查者对FAZ进行手动测量，并获得检查者间和检查者内的可靠性数据。
结果
个体测量的检查者间可靠性的组内相关系数（ICC）为0.62（中等），95%置信区间（CI）为0.40至0.79（p < 0.001）。检查者A的检查者内可靠性ICC（95%CI）为0.92（0.82至0.96），检查者B为0.96（0.91至0.98），检查者C为0.88（0.76至0.94）（p < 0.001）。在所有包括水肿情况和阻塞类型的亚分析中，检查者间可靠性为差/中等，检查者内可靠性为好/优秀。
结论
RVO患者的FAZ在不同眼睛之间差异显著，因此由于不同检查者之间的可靠性水平中等，使用OCTA获得的测量结果应谨慎分析。
Zotero 插件