Yamamoto Kazuki, Shiratori Yasutoshi, Ikeya Takashi
Division of Gastroenterology, St. Luke's International Hospital, Tokyo, Japan.
Clin Endosc. 2021 Mar;54(2):256-260. doi: 10.5946/ce.2020.081. Epub 2020 Aug 11.
BACKGROUND/AIMS: In Asia, right-sided diverticular bleeding is more common than that of the left side. It often causes massive bleeding and difficulties in identifying the stigmata of recent hemorrhage (SRH) of colonic diverticular bleeding (CDB). This case series demonstrates the efficacy of the gel immersion method using OS-1 Jelly (Otsuka Pharmaceuticals Factory, Tokushima, Japan) in patients with CDB.
This retrospective case series analyzed data of patients with CDB who underwent the gel immersion method from April 2016 to February 2020 at St. Luke's International Hospital, Japan. All patients diagnosed with CDB who underwent the gel immersion method were included. We collected data on the site of bleeding, identification of SRH, and efficacy of the method from the electronic medical records.
A total of 9 patients (including 7 with right-sided CDB) underwent gel immersion method and were included in this study. SRH were successfully found in 66.7% (6/9) of patients. Moreover, effective hemostasis was achieved in 85.7% (6/7) of patients with right-sided CDB. There were no adverse events.
The gel immersion method was found to be effective, especially for massive right-sided CDB.
背景/目的：在亚洲，右侧结肠憩室出血比左侧更为常见。它常导致大量出血，且难以识别结肠憩室出血（CDB）的近期出血征象（SRH）。本病例系列展示了使用大冢制药株式会社（日本德岛）生产的OS-1凝胶在CDB患者中采用凝胶浸泡法的疗效。
本回顾性病例系列分析了2016年4月至2020年2月在日本圣路加国际医院接受凝胶浸泡法治疗的CDB患者的数据。纳入所有诊断为CDB并接受凝胶浸泡法治疗的患者。我们从电子病历中收集了出血部位、SRH的识别情况以及该方法的疗效数据。
共有9例患者（包括7例右侧CDB患者）接受了凝胶浸泡法并纳入本研究。66.7%（6/9）的患者成功发现了SRH。此外，85.7%（6/7）的右侧CDB患者实现了有效止血。未发生不良事件。
发现凝胶浸泡法有效，尤其是对于大量右侧CDB。
