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肥胖与抑郁症:其患病率及作为预后因素的影响:一项系统综述

Obesity and Depression: Its Prevalence and Influence as a Prognostic Factor: A Systematic Review.

作者信息

Blasco Beatriz Villagrasa, García-Jiménez Jesús, Bodoano Isabel, Gutiérrez-Rojas Luis

机构信息

Psychogeriatry Area, Benito Menni CASM, Barcelona, Spain.

Psychiatry Service, Hospital General Básico Santa Ana, Motril, Granada, Spain.

出版信息

Psychiatry Investig. 2020 Aug;17(8):715-724. doi: 10.30773/pi.2020.0099. Epub 2020 Aug 12.

Abstract

OBJECTIVE

Depression and obesity are two conditions with great impact over global health. This is mainly due to their high prevalence and the morbidity and mortality associated to both. The main aim of the present systematic review is to study the association between obesity and depression and the prognostic implications derived from it.

METHODS

A literature review was performed in the PUBMED database. 18 articles were found (9 cross-sectional studies, 6 longitudinal studies and 3 clinical trials), which were reviewed by critical reading after which a summary of the main conclusions was written.

RESULTS

These selected articles confirmed that there is indeed a link between depression and obesity, although there are doubts as to the significance of this relationship. Depression is a risk factor for obesity, especially atypical depression and in African-American adolescent males. Obesity is a risk factor for depression, especially in women and for recurrent depressive disorder. The comorbidity between obesity and depression is a risk factor for a bad prognosis illness.

CONCLUSION

The relationship between both disorders has been analysed in scientific literature, obtaining significant associations but also contradictory results. The most current data demonstrates that there is a relationship between both entities, although there is no unanimity when it comes to establishing the meaning of this association.

摘要

目的

抑郁症和肥胖症是对全球健康有重大影响的两种疾病。这主要归因于它们的高患病率以及与之相关的发病率和死亡率。本系统评价的主要目的是研究肥胖症与抑郁症之间的关联及其预后意义。

方法

在PubMed数据库中进行文献综述。共检索到18篇文章(9篇横断面研究、6篇纵向研究和3篇临床试验),通过批判性阅读对这些文章进行评审,之后撰写主要结论总结。

结果

这些入选文章证实抑郁症与肥胖症之间确实存在关联,尽管这种关系的重要性存在疑问。抑郁症是肥胖症的一个危险因素,尤其是非典型抑郁症以及非裔美国青少年男性中的抑郁症。肥胖症是抑郁症的一个危险因素,尤其是在女性中以及对于复发性抑郁症而言。肥胖症与抑郁症的共病是疾病预后不良的一个危险因素。

结论

科学文献中已对这两种疾病之间的关系进行了分析,得出了显著关联但也有相互矛盾的结果。最新数据表明这两种疾病之间存在关联,尽管在确定这种关联的意义方面尚未达成一致。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa98/7449839/1097a60d6351/pi-2020-0099f1.jpg

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