Agarwal Amit, Pinho Marco, Raj Karuna, Yu Frank F, Bathla Girish, Achilleos Michael, ONeill Thomas, Still Michael, Maldjian Joseph
University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX, 75390, USA.
University of Iowa, 200 Hawkins Dr, Iowa City, IA, 52242, USA.
Emerg Radiol. 2020 Dec;27(6):747-754. doi: 10.1007/s10140-020-01837-7. Epub 2020 Aug 11.
Novel coronavirus disease (COVID-19) was declared a global pandemic on March 1, 2020. Neurological manifestations are now being reported worldwide, including emergent presentation with acute neurological changes as well as a comorbidity in hospitalized patients. There is limited knowledge on the neurologic manifestations of COVID-19 at present, with a wide array of neurological complications reported, ranging from ischemic stroke to acute demyelination and encephalitis. We report five cases of COVID-19 presenting to the ER with acute neurological symptoms, over the course of 1 month. This includes two cases of ischemic stroke, one with large-vessel occlusion and one with embolic infarcts. The remainders of the cases include acute tumefactive demyelination, isolated cytotoxic edema of the corpus callosum with subarachnoid hemorrhage, and posterior reversible encephalopathy syndrome (PRES).
2020年3月1日，新型冠状病毒病（COVID-19）被宣布为全球大流行。目前全球都在报告其神经学表现，包括以急性神经学变化为特征的紧急表现以及住院患者的合并症。目前关于COVID-19神经学表现的知识有限，已报告的神经学并发症种类繁多，从缺血性中风到急性脱髓鞘和脑炎。我们报告了在1个月内5例因急性神经症状到急诊就诊的COVID-19病例。其中包括2例缺血性中风，1例为大血管闭塞，1例为栓塞性梗死。其余病例包括急性瘤样脱髓鞘、胼胝体孤立性细胞毒性水肿伴蛛网膜下腔出血以及后部可逆性脑病综合征（PRES）。
