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The role of epsilon-aminocaproic acid in reducing bleeding after cardiac operation: a double-blind randomized study.

作者信息

Vander Salm T J, Ansell J E, Okike O N, Marsicano T H, Lew R, Stephenson W P, Rooney K

机构信息

Department of Surgery, University of Massachusetts Medical Center, Worcester 01655.

出版信息

J Thorac Cardiovasc Surg. 1988 Mar;95(3):538-40.

PMID:3278170
Abstract

Sixty patients scheduled for elective coronary artery bypass graft operations were randomly assigned to receive epsilon-aminocaproic acid or placebo to test whether antifibrinolytic therapy would decrease postoperative bleeding. A small but significant decrease in bleeding was observed in the treated group without complications resulting from treatment with epsilon-aminocaproic acid.

摘要

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The role of epsilon-aminocaproic acid in reducing bleeding after cardiac operation: a double-blind randomized study.
J Thorac Cardiovasc Surg. 1988 Mar;95(3):538-40.
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Effect of tranexamic acid on blood loss reduction after cardiopulmonary bypass.
氨甲环酸对体外循环后减少失血的作用。
Jpn J Thorac Cardiovasc Surg. 2001 May;49(5):273-8. doi: 10.1007/BF02913132.
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Drug Saf. 1998 Jan;18(1):21-41. doi: 10.2165/00002018-199818010-00003.
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Antifibrinolytic therapy in cardiac surgery.心脏手术中的抗纤溶治疗。
Tex Heart Inst J. 1995;22(3):211-5.
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Aprotinin. A review of its pharmacology and therapeutic efficacy in reducing blood loss associated with cardiac surgery.抑肽酶。其药理学及减少心脏手术相关失血的治疗效果综述。
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