Vander Salm T J, Ansell J E, Okike O N, Marsicano T H, Lew R, Stephenson W P, Rooney K
Department of Surgery, University of Massachusetts Medical Center, Worcester 01655.
J Thorac Cardiovasc Surg. 1988 Mar;95(3):538-40.
Sixty patients scheduled for elective coronary artery bypass graft operations were randomly assigned to receive epsilon-aminocaproic acid or placebo to test whether antifibrinolytic therapy would decrease postoperative bleeding. A small but significant decrease in bleeding was observed in the treated group without complications resulting from treatment with epsilon-aminocaproic acid.