Laboratory of Nutrition, Exercise and Health (LaNES), School of Medicine, Federal University of Uberlandia (UFU), Uberlandia, Minas Gerais 38400-902, Brazil.
School of Medicine, Federal University of Uberlandia (UFU), Uberlandia, Minas Gerais 38400-902, Brazil.
Nutrients. 2020 Aug 10;12(8):2390. doi: 10.3390/nu12082390.
Our aim was to associate serum uric acid (UA) with muscle mass, strength and functional capacity in kidney transplant patients (KTPs).
A cross-sectional study was performed on 113 KTPs. The fat-free mass and total and appendicular muscle mass were estimated by performing a bioelectrical impedance analysis. The strength was evaluated using the handgrip strength test (HGS) and the five times sit to stand test (5STS). The functional capacity was evaluated using the 4 m walk test and the short physical performance battery (SPPB).
Linear regression showed that the UA levels were positively associated with the muscle mass, fat-free mass, appendicular muscle mass, muscle mass index and appendicular muscle mass index. The 5STS results (seconds) were inversely associated with the UA levels, showing that individuals with higher UA were more likely to have more strength. However, UA was not associated with the HGS, 4 m walk test and SPPB results.
UA levels were positively associated with muscle mass and strength, but not with functional capacity, in KTPs.
本研究旨在探讨血清尿酸（UA）与肌肉量、力量和肾功能的相关性。
本研究为横断面研究，共纳入 113 例肾移植患者。采用生物电阻抗分析法评估无脂肪质量、总体肌肉量和四肢肌肉量。通过握力测试（HGS）和五次坐站测试（5STS）评估力量。4 米步行测试和简易体能状况量表（SPPB）用于评估功能能力。
线性回归分析显示，UA 水平与肌肉量、无脂肪质量、四肢肌肉量、肌肉量指数和四肢肌肉量指数呈正相关。5STS 结果（秒）与 UA 水平呈负相关，表明 UA 水平较高的个体可能具有更强的力量。然而，UA 与 HGS、4 米步行测试和 SPPB 结果无关。
UA 水平与肌肉量和力量呈正相关，但与肾功能无关。
